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This section outlines crucial safety information regarding the use of this medication. It's important to read these details thoroughly and discuss any concerns with your healthcare provider.

• Aluminum Absorption: Sucralfate (Carafate) includes a small amount of aluminum, which can be absorbed into the body via the stomach. Typically, the kidneys can eliminate excess aluminum from this medication and any aluminum-based antacids or supplements.
• Increased Risk: Individuals with a history of kidney issues or those taking other aluminum-containing products should exercise caution.

Please note that there are no specific contraindications listed for this medication.

Common side effects:

• Constipation
• Diarrhea
• Nausea
• Vomiting
• Upset stomach
• Dry mouth
• Itching
• Dizziness
• Headache
• Rash

Sucralfate is a medication commonly prescribed to treat and prevent ulcers in the digestive tract. While effective, it can interact with various other medications, potentially affecting their absorption and efficacy. Understanding these interactions is crucial for ensuring optimal treatment outcomes.

Common Drug Interactions:

• Antacids: Taking antacids within 30 minutes of sucralfate can reduce its effectiveness by impairing its ability to bind to the stomach lining. It's advisable to separate the administration of antacids and sucralfate by at least 30 minutes.

• Antibiotics: Sucralfate can decrease the absorption of certain antibiotics, such as fluoroquinolones (e.g., Ciprofloxacin, Levofloxacin) and tetracyclines. To minimize this interaction, these antibiotics should be taken at least two hours before or after sucralfate.

• Digoxin: This heart medication's absorption may be reduced when taken with sucralfate. To prevent this, administer digoxin at least two hours before sucralfate.

• Levothyroxine: Used for thyroid conditions, levothyroxine's effectiveness can be diminished by sucralfate. It's recommended to take levothyroxine at least four hours apart from sucralfate.

• Warfarin: Sucralfate may interfere with the absorption of warfarin, a blood thinner, potentially altering its effectiveness. Close monitoring of blood clotting levels (INR) may be necessary, and it's advisable to separate the administration times by at least two hours.

• Phenytoin: An anti-seizure medication, phenytoin's absorption can be decreased by sucralfate. To avoid this, take phenytoin at least two hours before or after sucralfate.

Food Interactions:

Food can interfere with the absorption of sucralfate, making it less effective. To avoid this interaction, it's important to take sucralfate on an empty stomach, at least one hour before or two hours after eating.

Recommendations:

To ensure the effectiveness of sucralfate and other medications:

• Timing: Administer sucralfate on an empty stomach, and space out the intake of interacting medications as recommended.

• Consultation: Always inform your healthcare provider about all medications, supplements, and over-the-counter drugs you are taking to assess potential interactions.

• Monitoring: Regularly monitor therapeutic levels and effectiveness of medications that may interact with sucralfate, adjusting dosages as necessary under medical supervision.

By adhering to these guidelines, you can minimize the risk of interactions and ensure that all your medications work effectively.