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Omeprazole-sodium Bicarbonate

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This medication is a combination of omeprazole and sodium bicarbonate. It is used to treat certain stomach and esophagus problems (such as acid reflux, ulcers). It is also used to prevent stomach bleeding in very ill patients. Omeprazole works by decreasing the amount of acid your stomach makes. It belongs to a class of drugs known as proton pump inhibitors (PPIs). Sodium bicarbonate is an antacid that reduces stomach acid and helps omeprazole to work better. This medication relieves symptoms such as heartburn, difficulty swallowing, and cough. It helps heal acid damage to the stomach and esophagus, helps prevent ulcers, and may help prevent cancer of the esophagus. If you are self-treating with this medication, over-the-counter omeprazole/sodium bicarbonate products are used to treat frequent heartburn (occurring 2 or more days a week). Since it may take 1 to 4 days to have full effect, these products do not relieve heartburn right away. For over-the-counter products, carefully read the package instructions to make sure the product is right for you. Check the ingredients on the label even if you have used the product before. The manufacturer may have changed the ingredients. Also, products with similar brand names may contain different ingredients meant for different purposes. Taking the wrong product could harm you.
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20-1100MG, Omeprazole-sodium Bicarbonate (30 Capsules)

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Omeprazole-sodium Bicarbonate Side Effects

Headache or abdominal pain may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. If your doctor has directed you to use this product, remember that your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor right away if you have any serious side effects, including: swelling of the hands/feet, symptoms of a low magnesium blood level (such as muscle spasms, irregular heartbeat, seizures), sudden weight gain, signs of lupus (such as rash on nose and cheeks, new or worsening joint pain), signs of kidney problems (such as change in the amount of urine, pink/bloody urine). When taken with sodium bicarbonate, large doses of calcium from your diet, medications, or supplements can rarely cause a serious problem called milk-alkali syndrome. Ask your doctor or pharmacist about using calcium products safely while you are using this medication. Tell your doctor right away if any of these serious side effects occur: dizziness, muscle aches/spasms, mental/mood changes (such as confusion, irritability, memory problems), vomiting, weakness. This medication may rarely cause a severe intestinal condition due to a bacteria called C. difficile. This condition may occur during treatment or weeks to months after treatment has stopped. Tell your doctor right away if you develop: diarrhea that doesn't stop, abdominal or stomach pain/cramping, blood/mucus in your stool. If you have these symptoms, do not use anti-diarrhea or opioid products because they may make symptoms worse. Rarely, proton pump inhibitors (such as omeprazole) have caused vitamin B-12 deficiency. The risk is increased if they are taken every day for a long time (3 years or longer). Tell your doctor right away if you develop symptoms of vitamin B-12 deficiency (such as unusual weakness, sore tongue, or numbness/tingling of the hands/feet). A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: fever, swollen lymph nodes, rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Interactions

Some products that may interact with this drug include: clopidogrel, mavacamten, memantine, methotrexate (especially high-dose treatment), rifampin, St John's wort. Some products need stomach acid so that the body can absorb them properly. Omeprazole/sodium bicarbonate decreases stomach acid, so it may change how well these products work. Some affected products include atazanavir, erlotinib, levoketoconazole, nelfinavir, pazopanib, rilpivirine, sparsentan, certain azole antifungals (itraconazole, ketoconazole, posaconazole), among others. Omeprazole is very similar to esomeprazole. Do not use any medications containing esomeprazole while using omeprazole. This medication may interfere with certain lab tests, possibly causing false test results. Make sure lab personnel and all your doctors know you use this drug.
Omeprazole-sodium Bicarbonate FAQs
What does sodium bicarbonate do for the stomach?

Sodium bicarbonate acts as an antacid in the stomach. It helps to neutralize stomach acid, providing relief from symptoms such as heartburn, indigestion, and upset stomach. By increasing the pH level in the stomach, it can alleviate discomfort associated with excess stomach acid.

Sodium bicarbonate is used to treat conditions related to excess stomach acid, such as heartburn, indigestion, and upset stomach. It is also used to make the blood or urine less acidic in certain medical conditions. Additionally, it can be used in emergency situations to treat certain types of drug overdoses or poisoning.

When taking omeprazole, it is advisable to avoid the following:1. Alcohol: It can increase stomach acid production and irritate the stomach lining, potentially reducing the effectiveness of omeprazole.2. Certain Foods: Spicy, fatty, or acidic foods may exacerbate symptoms of acid reflux or heartburn, counteracting the benefits of omeprazole.3. NSAIDs: Nonsteroidal anti-inflammatory drugs, such as ibuprofen or aspirin, can irritate the stomach lining and should be used cautiously.4. Smoking: Smoking can increase stomach acid production and delay healing of the stomach lining.5. Certain Medications: Some medications may interact with omeprazole, such as clopidogrel, certain antifungals, and HIV medications. It is important to consult with a healthcare provider about potential interactions.6. Grapefruit and Grapefruit Juice: These can interfere with the metabolism of omeprazole, potentially affecting its efficacy.It is always best to discuss any concerns or potential interactions with a healthcare provider.

When taking omeprazole, it is generally advisable to avoid foods and beverages that can irritate the stomach or increase acid production. These include:- Spicy foods- Acidic foods like citrus fruits and tomatoes- Caffeinated beverages such as coffee and tea- Carbonated drinks- AlcoholAdditionally, it may be beneficial to avoid large meals and eating late at night to help manage symptoms effectively. Always consult with a healthcare provider for personalized dietary advice.

Sodium bicarbonate is used in emergency situations to treat metabolic acidosis, which can occur in conditions such as cardiac arrest, severe dehydration, or kidney failure. It is also used to manage certain drug overdoses, such as tricyclic antidepressant overdose, by alkalinizing the urine to enhance drug elimination. Additionally, it can be used to treat hyperkalemia by shifting potassium into cells.

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