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Omeprazole-sodium Bicarbonate

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generic Zegerid, Zegerid Otc, Cvs Omeprazole-sod Bicarbonate, Konvomep, Goodsense Omep/sod Bicarb

Zegerid is a combination medication consisting of omeprazole and sodium bicarbonate, designed to manage conditions caused by excessive stomach acid. It is primarily used to treat and provide relief from heartburn, stomach ulcers, duodenal ulcers, gastroesophageal reflux disease (GERD), and erosive esophagitis. Additionally, it helps reduce the risk of stomach bleeding in severely ill patients, particularly in a hospital setting. Omeprazole, a proton pump inhibitor (PPI), functions by decreasing the production of stomach acid, while sodium bicarbonate acts as an antacid, enhancing the effectiveness of omeprazole. This combination alleviates symptoms like heartburn, difficulty swallowing, and persistent cough, and aids in healing acid damage in the stomach and esophagus. It is also beneficial in preventing ulcers and potentially reducing the risk of esophageal cancer. Available in a powder form that can be transformed into a liquid suspension for those who have difficulties swallowing pills, Zegerid is typically taken once daily by mouth. It is crucial to follow your healthcare provider’s recommendations regarding the duration of use to avoid potential side effects such as bone fractures or low magnesium levels. For those using over-the-counter versions of this medication for frequent heartburn (occurring two or more days a week), it is important to note that it may take one to four days to achieve full effectiveness and is not intended for immediate heartburn relief. Always read the package instructions carefully and consult a healthcare professional to ensure the product is suitable for you.
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20-1100MG, Omeprazole-sodium Bicarbonate (30 Capsules)

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CVS

$32.58

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$23.18

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$29.95

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$57.50

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$323.74

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Omeprazole-sodium Bicarbonate savings card

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Omeprazole-sodium Bicarbonate dosage forms

The average cost for 30 Capsules of Omeprazole-sodium Bicarbonate (generic Zegerid, Zegerid Otc, Cvs Omeprazole-sod Bicarbonate, Konvomep, Goodsense Omep/sod Bicarb) at 20-1100MG is $29.95 with a free coupon. This is 2.39% off the average retail price of $1251.26
DosageQuantityPrice fromPer unit
20-1100MG30 Capsules$29.95$1
40-1100MG30 Capsules$21.16$0.71

Omeprazole-sodium Bicarbonate Warnings

The following safety information outlines potential risks and important precautions for using Zegerid (omeprazole / sodium bicarbonate). Review these points carefully and discuss any concerns with your healthcare provider.

  • Consultation Needed: If your symptoms are initially relieved by Zegerid but then return, consult your healthcare provider. Recurring symptoms could indicate a more serious condition, such as stomach cancer, requiring further investigation.

  • Kidney Damage: There is a potential risk of kidney damage during treatment with proton pump inhibitors (PPIs) like omeprazole. Symptoms such as blood in the urine, altered urination patterns, nausea, fever, or confusion require immediate medical consultation.

  • Severe Skin Reactions: Rare but serious skin reactions, including Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN), may occur. Seek immediate medical attention if flu-like symptoms accompany skin rash, blisters, or peeling.

  • High Sodium Content: Zegerid contains sodium, which may lead to swelling and weight gain. Patients on low-sodium diets or with conditions like heart failure or hypertension should consult their provider before use.

  • Acid-Base Imbalance: Extended use or combination with calcium supplements or milk can lead to Milk-alkali syndrome, affecting kidney function. Symptoms such as nausea, frequent urination, headache, or dizziness warrant a discussion with your provider.

  • Severe Diarrhea: This medication can increase the risk of bacterial infections causing severe diarrhea. If experiencing persistent watery diarrhea, fever, or stomach pain, contact your healthcare provider. Minimize risk by using the lowest effective dose for the shortest necessary duration.

  • Bone Fractures: Long-term or high-dose use of Zegerid may increase fracture risk. Consider vitamin D and calcium supplementation and discuss bone health strategies with your provider.

  • Lupus Risk: PPIs might trigger or exacerbate lupus, with symptoms potentially appearing from weeks to years. Minimize risk by using the lowest effective dose for the shortest time. Consult your provider about symptom monitoring.

  • Drug Interactions: Zegerid can interact with numerous medications, including warfarin, methotrexate, and some HIV treatments. Inform your healthcare provider and pharmacist of all medications, vitamins, and supplements you are taking to avoid adverse interactions.

  • Nutrient Deficiencies: Long-term use (over a year for magnesium and over three years for vitamin B12) may lead to deficiencies. Monitor levels if using Zegerid for extended periods.

  • Stomach Growths: Rarely, prolonged use can result in small stomach growths. Minimize treatment duration to mitigate this risk.

Contraindications: Do not use Zegerid if you are taking rilpivirine-containing medications or have a known allergy to benzimidazoles. Always consult your healthcare provider if these conditions apply.

Omeprazole-sodium Bicarbonate Side Effects

Common side effects:

  • headaches
  • stomach pain
  • diarrhea
  • nausea
  • gas
  • vomiting

Less common but important to monitor:

  • dizziness
  • rash
  • constipation
  • lack of energy
  • symptoms of an upper respiratory infection

Serious side effects:

  • severe diarrhea
  • serious kidney issues
  • severe skin reaction
  • low magnesium levels
  • severe intestinal condition caused by C. difficile
  • vitamin B-12 deficiency
  • severe allergic reactions

Omeprazole-sodium Bicarbonate Interactions

Interactions with high risk of serious adverse effects and should be avoided:

  • Rilpivirine
  • Esomeprazole

Interactions with moderate risk that may require dose adjustment, closer monitoring, or timing changes:

Interactions with low risk that usually do not require a change in therapy:

Omeprazole-sodium Bicarbonate FAQs
What does sodium bicarbonate do for the stomach?

Sodium bicarbonate acts as an antacid in the stomach. It helps to neutralize stomach acid, providing relief from symptoms such as heartburn, indigestion, and upset stomach. By increasing the pH level in the stomach, it can alleviate discomfort associated with excess stomach acid.

Sodium bicarbonate is used to treat conditions related to excess stomach acid, such as heartburn, indigestion, and upset stomach. It is also used to make the blood or urine less acidic in certain medical conditions. Additionally, it can be used in emergency situations to treat certain types of drug overdoses or poisoning.

When taking omeprazole, it is advisable to avoid the following:1. Alcohol: It can increase stomach acid production and irritate the stomach lining, potentially reducing the effectiveness of omeprazole.2. Certain Foods: Spicy, fatty, or acidic foods may exacerbate symptoms of acid reflux or heartburn, counteracting the benefits of omeprazole.3. NSAIDs: Nonsteroidal anti-inflammatory drugs, such as ibuprofen or aspirin, can irritate the stomach lining and should be used cautiously.4. Smoking: Smoking can increase stomach acid production and delay healing of the stomach lining.5. Certain Medications: Some medications may interact with omeprazole, such as clopidogrel, certain antifungals, and HIV medications. It is important to consult with a healthcare provider about potential interactions.6. Grapefruit and Grapefruit Juice: These can interfere with the metabolism of omeprazole, potentially affecting its efficacy.It is always best to discuss any concerns or potential interactions with a healthcare provider.

When taking omeprazole, it is generally advisable to avoid foods and beverages that can irritate the stomach or increase acid production. These include:- Spicy foods- Acidic foods like citrus fruits and tomatoes- Caffeinated beverages such as coffee and tea- Carbonated drinks- AlcoholAdditionally, it may be beneficial to avoid large meals and eating late at night to help manage symptoms effectively. Always consult with a healthcare provider for personalized dietary advice.

Sodium bicarbonate is used in emergency situations to treat metabolic acidosis, which can occur in conditions such as cardiac arrest, severe dehydration, or kidney failure. It is also used to manage certain drug overdoses, such as tricyclic antidepressant overdose, by alkalinizing the urine to enhance drug elimination. Additionally, it can be used to treat hyperkalemia by shifting potassium into cells.