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This medication carries several important safety warnings and precautions that must be considered before use. It is crucial to understand the potential risks and consult a healthcare provider with any concerns.

• Risk to Unborn Babies: Using this medication during pregnancy can be extremely harmful, potentially causing severe or life-threatening effects to an unborn child. It's essential to avoid pregnancy while taking this medication. If you are pregnant, planning to become pregnant, or suspect you might be pregnant, inform your doctor immediately. Your healthcare provider can discuss alternative treatments to manage your condition safely.

• Low Blood Pressure: This medication may cause your blood pressure to drop too much, leading to symptoms such as dizziness, fatigue, or lightheadedness, particularly when starting or increasing the dose. Ensure you are well-hydrated to help manage blood pressure levels. If you experience significant dizziness, sit down slowly and contact your healthcare provider. Seek immediate medical attention if you fall and hit your head. People with insufficient body fluids, prolonged diarrhea or vomiting, low salt levels, high doses of diuretics, or a history of narrow heart valves are at a higher risk.

• High Potassium Levels: The medication can elevate potassium levels in the blood, which may be dangerous. This risk increases if you are taking other medications that raise potassium, such as spironolactone. Regular blood tests will be conducted to monitor potassium levels. Notify your healthcare provider if you experience symptoms like nausea, muscle weakness, or irregular heartbeat.

• Increased Risk of Heart Attack or Chest Pain: Some individuals might experience worsening chest pain or a heart attack, especially when beginning this treatment or increasing the dose. Those with severe coronary artery disease are at higher risk. Immediate medical attention is necessary if you experience symptoms such as chest pain, pressure, heartburn, dizziness, or difficulty breathing.

• Potential Kidney Damage: This medication may impair kidney function, particularly in individuals with pre-existing kidney issues, such as renal artery stenosis or severe heart failure. Regular laboratory tests may be required to monitor kidney health. Consult your provider if you notice reduced urination, as this could indicate kidney problems.

• Contraindications: This medication should not be used in conjunction with aliskiren (Tekturna) if you have diabetes, as it poses significant health risks.

Always discuss your medical history and any other medications you are taking with your healthcare provider to ensure safe and effective use of this medication.

Common side effects:

• Swelling of the hands, ankles, or feet
• Dizziness
• Back pain

Less common but important to monitor:

• High potassium levels
• Muscle-related issues like stiffness, tremor, or abnormal movements

Serious side effects:

• Fainting
• Low blood pressure
• Symptoms indicative of heart problems such as chest pain, tightness, cold and clammy skin, and irregular heartbeat
• Severe allergic reactions characterized by rash, itching, swelling of the face, tongue, or throat, severe dizziness, or difficulty breathing

When taking Telmisartan / Amlodipine, it is important to be aware of potential interactions with other medications. Some drugs, like Aliskiren, should not be combined with this medication. Other medications, such as Benazepril, Lisinopril, and Lithium, may require special consideration or dosage adjustments if they are used together with Telmisartan / Amlodipine. Additionally, medications that can raise potassium levels in the blood, including sparsentan and certain birth control pills containing drospirenone, may interact and require caution.

Inform your healthcare provider about all prescription and over-the-counter medications, vitamins, and supplements you are taking. Some products, notably those for cough and cold, diet aids, or NSAIDs like Ibuprofen and Naproxen, might increase blood pressure and should be used carefully. Your doctor or pharmacist can guide you on how to manage these interactions safely to ensure effective and safe treatment.