Lisinopril-hydrochlorothiazide Coupons & Savings Card – Discount Prices from $3.49

Lisinopril, particularly when part of Zestoretic (lisinopril/hydrochlorothiazide), requires careful consideration due to several associated risks and contraindications. Below are important safety precautions and warnings to keep in mind when using this medication.

• Pregnancy Warning: Lisinopril can result in severe and potentially fatal harm to an unborn child. It is crucial to avoid becoming pregnant while on this medication. If you become pregnant or plan to become pregnant, contact your healthcare provider immediately to discuss alternative treatments.

• Angioedema Risk: Use of lisinopril can lead to angioedema, a rare but serious condition characterized by swelling of the face, throat, or tongue, which can obstruct breathing and require immediate medical intervention. This risk is heightened in individuals of Black descent and those with a history of angioedema. Discontinue use and seek urgent medical attention if you experience such symptoms.

• Low Blood Pressure: Zestoretic may cause a significant drop in blood pressure, resulting in dizziness, fatigue, or lightheadedness, particularly at the start of treatment or with dose increases. To mitigate these effects, stay hydrated and get up slowly from sitting or lying positions. Contact your healthcare provider if symptoms persist or if you experience a fall due to dizziness.

• Kidney Health: The medication can impair kidney function, especially in patients with pre-existing kidney issues or severe heart failure. Regular monitoring of kidney function through lab tests may be necessary. Reduced urine output can signal kidney problems, warranting immediate consultation with your healthcare provider.

• Electrolyte and Metabolic Changes: Zestoretic can alter electrolyte levels and affect blood sugar and cholesterol. Regular blood tests may be conducted to monitor these levels. Notify your healthcare team if you experience rapid heartbeat, muscle cramps, weakness, or digestive issues, as these could indicate electrolyte imbalances.

• Vision Changes: In rare cases, the hydrochlorothiazide component may cause vision problems soon after commencing treatment. Report any visual disturbances or eye pain to your healthcare provider promptly, as intervention may be needed to prevent permanent damage.

• Lupus Consideration: Though uncommon, Zestoretic may exacerbate lupus or induce lupus-like symptoms. Be vigilant for facial rashes or extreme fatigue and inform your healthcare provider if they occur.

Contraindications:

• Do not use Zestoretic if you are taking aliskiren (Tekturna) and have diabetes.
• Avoid use with neprilysin inhibitors like Entresto (sacubitril/valsartan) or within 36 hours of taking them.
• This medication is not suitable for individuals who do not produce urine or have allergies to sulfa drugs, ACE inhibitors, or a history of angioedema.

Always consult your healthcare provider with any concerns or questions regarding the use of this medication to ensure it is safe and effective for your specific health needs.

Common side effects:

• dizziness
• headache
• tiredness

• dry cough

  Less common but important to monitor:

• chest pain
• stomach cramps
• constipation
• dry mouth
• muscle cramps
• lower sex drive

• ringing in the ears

  Serious side effects:

• severe swelling (angioedema)
• dangerously low blood pressure
• serious kidney issues
• liver problems
• high blood potassium levels
• dehydration and electrolyte imbalances
• very serious allergic reaction

Interactions with high risk of serious adverse effects and should be avoided:

• Aliskiren
• Dofetilide
• Sacubitril

Interactions with moderate risk that may require dose adjustment, closer monitoring, or timing changes:

• NSAIDs (e.g., Ibuprofen, Naproxen)
• Losartan
• Valsartan
• Everolimus
• Sirolimus
• Lithium
• Droperidol
• Eplerenone
• Potassium
• Triamterene