Trikafta

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Trikafta is an oral medication designed to treat cystic fibrosis in individuals aged 2 years and older who have specific genetic mutations. Comprising three active ingredients—elexacaftor, tezacaftor, and ivacaftor—Trikafta works by targeting and modulating the cystic fibrosis transmembrane conductance regulator (CFTR) proteins. This helps correct the abnormal proteins caused by genetic mutations, which can reduce mucus buildup in the lungs, improve breathing, minimize the risk of lung infections, and assist with weight gain. Common side effects may include headaches, stomach pain, and an increased likelihood of respiratory infections, such as the common cold, as well as acne. Always consult with a healthcare professional for advice tailored to your medical needs before starting any new medication.
Our Trikafta coupons are free to use. You can print the coupon, email it to yourself, or receive the Trikafta coupon via text message. To get your free discount, show the pharmacist your Trikafta savings card which has the discounted coupon price. Use our filters below to edit the prescription box to match your needs. The Trikafta prices will update based on your prescription needs. Above our Trikafta coupons, you can change the location to see pharmacy prices in other areas. Our prescription discount card will update online with the specific pharmacy costs associated with your edits. Be sure to text, email, or print the Trikafta savings card code that you need after editing the prescription box and location field. Show the discount card to your pharmacist before paying.

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100-50-75 & 150MG, Trikafta (30 Tablet Therapy Packs)

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Rite Aid

$9433.80

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Walgreens

$9832.98

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Trikafta savings card

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Rite Aid

$9433.80

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Trikafta dosage forms

The average cost for 30 Tablet Therapy Packs of Trikafta at 100-50-75 & 150MG is $9558.31 with a free coupon. This is 27.95% off the average retail price of $34203.6
DosageQuantityPrice fromPer unit
100-50-75 & 150MG30 Tablet Therapy Packs$9558.31$318.61
50-25-37.5 & 75MG30 Tablet Therapy Packs$9558.31$318.61

Trikafta Warnings

This medication may rarely cause serious (possibly fatal) liver problems. Before and during treatment with this medication, you will have certain blood tests (liver function) to monitor for liver problems. Keep all medical and lab appointments. Get medical help right away if you have any symptoms of liver damage, such as: nausea/vomiting that doesn't stop, stomach/abdominal pain, dark urine, loss of appetite, yellowing eyes/skin.

Trikafta Side Effects

When taking this medication, some individuals may experience mild side effects such as headaches, diarrhea, or dizziness. These are generally not a cause for concern, but if they persist or worsen, it is advisable to consult a healthcare provider. Other common side effects include upper respiratory tract infections, stomach pain, stuffy or runny nose, flu-like symptoms, and sinus infections. While rashes are relatively common and often not serious, they should be monitored closely, as they could indicate a more severe reaction.

Less frequent side effects include gas, bloating, pink eye, sore throat, urinary tract infections, changes in menstrual periods, and skin reactions such as acne or eczema. Some individuals may also experience higher blood pressure. These side effects are usually manageable, but should they become troublesome, medical advice should be sought.

In rare cases, serious side effects can occur, requiring immediate medical attention. Symptoms of a severe allergic reaction include rash, itching, swelling of the face, tongue, or throat, severe dizziness, and trouble breathing. Liver damage, indicated by pain in the upper right stomach area, dark urine, pale stools, or yellowing of the skin or eyes, is also serious and demands urgent care. If you experience any unlisted side effects or have concerns, contacting a healthcare professional is recommended.

Trikafta Interactions

Certain medications can alter the way elexacaftor, tezacaftor, and ivacaftor are eliminated from your body, potentially impacting their effectiveness. These include mifepristone, rifamycins (like rifampin and rifabutin), seizure medications (such as carbamazepine and phenytoin), and St. John's wort.
Trikafta FAQs
What exactly does Trikafta do?

Trikafta is a medication used to treat cystic fibrosis in patients with specific mutations in the CFTR gene. It works by improving the function of the defective CFTR protein, which helps to regulate the flow of salt and fluids in and out of cells. This can lead to improved lung function and reduced symptoms associated with cystic fibrosis.

The cost of Trikafta can vary significantly depending on factors such as insurance coverage, location, and pharmacy. However, the list price for Trikafta is approximately $311,000 per year. Patients are encouraged to consult with their healthcare provider or insurance company for more specific information regarding their individual costs and potential financial assistance programs.

Trikafta can potentially affect liver function. It is important for patients taking Trikafta to have their liver function monitored regularly through blood tests, especially if they have a history of liver disease. Any concerns or symptoms should be discussed with a healthcare provider.

The life expectancy of someone taking Trikafta can vary based on individual health factors and the progression of cystic fibrosis. Trikafta has been shown to significantly improve lung function and overall health outcomes in many patients, potentially extending life expectancy. However, specific life expectancy predictions should be discussed with a healthcare provider, as they can provide personalized information based on the individual's health status and response to treatment.

Trikafta can potentially cause liver damage. It is important for patients taking Trikafta to have their liver function monitored regularly through blood tests. If any signs of liver damage occur, such as jaundice or unusual fatigue, it is crucial to contact a healthcare provider immediately.