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When using Uribel Tabs, it is crucial to be aware of potential risks and safety precautions. Below are important points to consider, and it is advised to discuss any concerns with your healthcare provider:

• Mental and Nervous System Effects: Uribel Tabs may cause excitement, agitation, drowsiness, or confusion, particularly in individuals aged 65 and older. If these symptoms become bothersome, consult your prescriber.

• Serious Drug Interactions: If you are taking medications that increase serotonin levels, such as fluoxetine (Prozac), inform your healthcare provider before starting Uribel Tabs. The methylene blue in Uribel Tabs can prevent serotonin breakdown, potentially leading to serotonin syndrome, characterized by confusion, muscle twitching, shaking, and diarrhea.

• Allergic Reactions: Be cautious if you have previously had allergic reactions to belladonna alkaloids (e.g., atropine, scopolamine) or salicylates (e.g., aspirin). Notify your prescriber if you have a history of such allergies.

• Digestive Issues: Uribel Tabs may slow digestion, posing risks if you have a stomach ulcer. Ensure your prescriber is aware if you are being treated for a stomach ulcer.

• Long-Term Use: The safety of using Uribel Tabs over a prolonged period is not established. Discuss the potential risks and benefits of long-term use with your prescriber.

Please note there are no specific contraindications provided for Uribel Tabs. Always consult your healthcare provider for personalized advice.

When taking this medication, you may experience some common side effects, which are generally mild and should not cause alarm. These include nausea, vomiting, dry mouth, dizziness, drowsiness, and blurred vision. Some individuals also notice changes in urine or stool color to blue or blue-green, which is harmless and will disappear after stopping the medication. To alleviate dry mouth, consider sipping water, or using sugarless gum or candy.

There are more serious side effects that require prompt attention. If you notice hot, dry, flushed skin, decreased sweating, eye pain, difficulty urinating, or symptoms of kidney issues like changes in urine output or painful urination, contact your healthcare provider. Additionally, if you experience severe symptoms such as abdominal pain, easy bruising, black stools, or vomit that resembles coffee grounds, seek medical assistance immediately. These could be signs of serious conditions involving the liver or gastrointestinal tract.

In rare cases, this medication may cause a hypertensive crisis, a potentially life-threatening condition marked by severe headache, an irregular heartbeat, chest pain, and vision changes. If these occur, obtain medical help urgently. Allergic reactions are also rare but serious. Symptoms may include a rash, itching, severe dizziness, or swelling, particularly of the face, tongue, or throat, and trouble breathing. If you experience any of these, seek emergency medical care. Always report any unusual side effects to your healthcare provider for further advice.

This medication can interact with a variety of other products and medications. Some interactions include:

• Drugs and Products: This medication may interact with apraclonidine, atomoxetine, bupropion, carbamazepine, dichlorphenamide, methotrexate, mifepristone, potassium supplements, pramlintide, tetrabenazine, and certain drugs used to treat Parkinson's disease (entacapone, levodopa, tolcapone). It may also interact with blood pressure medications like guanethidine and methyldopa, sulfonamide drugs including certain antibiotics such as sulfamethoxazole, and sympathomimetics like amphetamine and ephedrine. Additionally, products that reduce acid in the urine (such as antacids and sodium bicarbonate) may also interact.

• Bleeding Risk: This medication can increase bleeding risk when used with other drugs that also cause bleeding, such as anti-platelet drugs like clopidogrel and blood thinners including dabigatran, enoxaparin, and warfarin.

• MAO Inhibitors: Taking other monoamine oxidase (MAO) inhibitors with this medication can result in a serious, potentially life-threatening interaction. Avoid using other MAO inhibitors during treatment and for two weeks before and after this medication. These include isocarboxazid, linezolid, moclobemide, phenelzine, rasagiline, and others.

• High Blood Pressure: Some drugs and herbal products can cause dangerously high blood pressure when used with this medication, including herbal supplements like ephedra, nasal decongestants such as phenylephrine, and stimulants like amphetamines.

• Azole Antifungals: If you're taking azole antifungal drugs such as itraconazole or ketoconazole, take this medication at least two hours after the antifungal.

• Pain Relievers/Fever Reducers: Many medications contain pain relievers or fever reducers (like aspirin or NSAIDs such as ibuprofen) that can increase side effects. If prescribed low-dose aspirin for heart attack or stroke prevention, continue as instructed by your doctor.

• Drowsiness: Inform your healthcare provider if you're using other products that cause drowsiness, including alcohol, marijuana, antihistamines, sleep or anxiety medications, muscle relaxants, and opioid pain relievers. Check the labels of all over-the-counter medications for drowsiness-inducing ingredients and consult with your pharmacist.

• Lab Tests: This medication may interfere with certain laboratory tests, potentially leading to false results. Ensure all healthcare providers and lab personnel are aware of your medication use.

Always discuss with your doctor or pharmacist for further details and guidance on managing these interactions safely.