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You may experience mild side effects such as nausea, vomiting, dry mouth, dizziness, drowsiness, blurred vision, or constipation. These effects are generally manageable and temporary. To alleviate a dry mouth, try sucking on sugarless candy or ice chips, chewing sugarless gum, drinking water, or using a saliva substitute. Additionally, this medication may cause urine and sometimes stools to appear blue-green, which is harmless and resolves after stopping the medication.

However, be alert for more serious side effects. Contact your healthcare provider immediately if you notice symptoms like hot, dry, or flushed skin, decreased sweating, eye pain, or difficulty urinating, as these may indicate more significant issues. There are also very serious side effects requiring urgent medical attention, including easy bruising or bleeding, black or tarry stools, severe abdominal pain, and vomiting that resembles coffee grounds. These could be signs of liver problems or other serious conditions.

In rare cases, this medication may trigger a hypertensive crisis, characterized by an extremely high blood pressure that could be life-threatening. Seek immediate medical help if you experience a severe headache, irregular heartbeat, chest pain, or severe nausea, as well as any changes in vision or sensitivity to light. Although an allergic reaction to this drug is rare, symptoms like a rash, swelling (especially of the face, tongue, or throat), severe dizziness, or difficulty breathing require prompt medical attention.

Always remain vigilant for any other unexpected effects and consult your healthcare provider for advice.

This medication can interact with several other products and medications. These include apraclonidine, atomoxetine, bupropion, carbamazepine, dichlorphenamide, methotrexate, mifepristone, potassium capsules/tablets, pramlintide, tetrabenazine, certain Parkinson's medications (like entacapone, levodopa, tolcapone), specific blood pressure medications (such as guanethidine, methyldopa), sulfonamide drugs (including sulfa antibiotics like sulfamethoxazole), and sympathomimetics (such as amphetamine, ephedrine). It can also interact with products that reduce urine acidity, such as antacids, sodium bicarbonate, potassium/sodium citrate, and acetazolamide.

This medication may increase bleeding risk if taken with other drugs that also cause bleeding, like anti-platelet medications such as clopidogrel and blood thinners like dabigatran, enoxaparin, or warfarin.

Combining this medication with other MAO inhibitors can lead to a severe and possibly fatal interaction. Avoid using other MAO inhibitors (such as isocarboxazid, linezolid, metaxalone, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, tranylcypromine) during treatment and for two weeks before and after using this medication. Consult your doctor about when to start or stop this medication.

Before using this product, inform your doctor about any other drugs you take that could significantly raise blood pressure (hypertensive crisis) when combined with this medication. This includes herbal products like ephedra (ma huang), nasal decongestants (such as phenylephrine, pseudoephedrine), stimulants (like amphetamines, ephedrine, epinephrine), and diet aids. Avoid using these with this medication and consult your doctor or pharmacist for further guidance.

If you're taking azole antifungals (such as itraconazole, ketoconazole), ensure there is a gap of at least two hours between taking these and this medication.

Carefully review labels on all prescription and non-prescription medicines because many contain pain relievers or fever reducers (e.g., aspirin, NSAIDs like ibuprofen, ketorolac, or naproxen), which are similar to salicylate and may increase side effects. If your doctor has prescribed low-dose aspirin for heart attack or stroke prevention (typically 81-162 milligrams daily), continue unless advised otherwise. Consult your doctor or pharmacist for more information.

Inform your doctor or pharmacist if you are using other products that cause drowsiness, including alcohol, marijuana (cannabis), antihistamines (such as cetirizine, diphenhydramine), sleep or anxiety medications (like alprazolam, diazepam, zolpidem), muscle relaxants, and opioid painkillers (such as codeine).

Examine all your medication labels (including allergy or cough-and-cold products) as they may contain ingredients inducing drowsiness. Discuss with your pharmacist how to use these products safely.

This medication may affect certain laboratory tests, possibly leading to false results. Ensure all your doctors and lab personnel know you are using this medication.