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Nausea, vomiting, dry mouth, dizziness, drowsiness, blurred vision, or constipation may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. To relieve dry mouth, suck on (sugarless) hard candy or ice chips, chew (sugarless) gum, drink water, or use a saliva substitute. This medication causes urine and sometimes stools to turn blue-green. This effect is harmless and will disappear when the medication is stopped. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor right away if you have any serious side effects, including: hot/dry/flushed skin, decreased sweating, eye pain, difficult urination, signs of kidney problems (such as change in the amount of urine, painful urination). Get medical help right away if you have any very serious side effects, including: easy bruising/bleeding, black/tarry stools, stomach/abdominal pain, vomit that looks like coffee grounds, signs of liver problems (such as nausea/vomiting that doesn't stop, unusual tiredness, dark urine, yellowing eyes/skin). This drug may rarely cause an attack of extremely high blood pressure (hypertensive crisis), which may be fatal. Many drug interactions can increase this risk (see Drug Interactions section). Get medical help right away if any of these serious side effects occur: severe headache, fast/slow/irregular/pounding heartbeat, chest pain, neck stiffness/soreness, severe nausea/vomiting, sweaty/clammy skin (sometimes with fever), widened pupils, vision changes (such as double/blurred vision), sudden sensitivity to light (photophobia). A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

This medication may interact with many products. Some products include: apraclonidine, atomoxetine, bupropion, carbamazepine, dichlorphenamide, methotrexate, mifepristone, potassium capsules/tablets, pramlintide, tetrabenazine, certain Parkinson's disease drugs (entacapone, levodopa, tolcapone), certain high blood pressure drugs (guanethidine, methyldopa), sulfonamide drugs (including sulfa antibiotics such as sulfamethoxazole), sympathomimetics (such as amphetamine, ephedrine), products that decrease the amount of acid in the urine (such as antacids, sodium bicarbonate, potassium/sodium citrate, acetazolamide). This medication may increase the risk of bleeding when taken with other drugs that also may cause bleeding. Examples include anti-platelet drugs such as clopidogrel, "blood thinners" such as dabigatran/enoxaparin/warfarin, among others. Taking other MAO inhibitors with this medication may cause a serious (possibly fatal) drug interaction. Avoid taking other MAO inhibitors (isocarboxazid, linezolid, metaxalone, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, tranylcypromine) during treatment with this medication. Most MAO inhibitors should also not be taken for two weeks before and after treatment with this medication. Ask your doctor when to start or stop taking this medication. Before using this product, report the use of other drugs that may increase the risk of extremely high blood pressure (hypertensive crisis) when combined with this product, including herbal products (such as ephedra/ma huang), nasal decongestants (such as phenylephrine, pseudoephedrine), stimulants (such as amphetamines, ephedrine, epinephrine), diet aids, among others. This product should not be used with any of these medications. Talk to your doctor or pharmacist for more details. If you are also taking azole antifungal drugs (such as itraconazole, ketoconazole), take this product at least 2 hours after the antifungal drug. Check all prescription and nonprescription medicine labels carefully since many medications contain pain relievers/fever reducers (aspirin, NSAIDs such as ibuprofen, ketorolac or naproxen). These drugs are similar to salicylate and may increase your risk of side effects if taken together. However, if your doctor has told you to take low-dose aspirin to prevent heart attack or stroke (usually 81-162 milligrams a day), you should keep taking the aspirin unless your doctor tells you not to. Ask your doctor or pharmacist for more details. Tell your doctor or pharmacist if you are taking other products that cause drowsiness including alcohol, marijuana (cannabis), antihistamines (such as cetirizine, diphenhydramine), drugs for sleep or anxiety (such as alprazolam, diazepam, zolpidem), muscle relaxants, and opioid pain relievers (such as codeine). Check the labels on all your medicines (such as allergy or cough-and-cold products) because they may contain ingredients that cause drowsiness. Ask your pharmacist about using those products safely. This medication may interfere with certain lab tests, possibly causing false test results. Make sure lab personnel and all your doctors know you use this drug.