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This medication comes with several important safety precautions and risks that need to be carefully considered. If you have any questions or concerns, consult your healthcare provider.

• Risk of Transfer and Early Puberty: Children may accidentally be exposed to testosterone gel through skin contact with the application site. This can lead to unwanted side effects such as early puberty signs in children or male characteristics in females. Ensure that the application area is covered and washed before contact with others, particularly children and women.

• Increased Red Blood Cell Count and Blood Clots: Testosterone gel can elevate red blood cell levels, which may result in blood clots. Regular blood tests may be necessary to monitor this condition.

• Cardiovascular Risks: The use of testosterone gel may increase the risk of heart attack, stroke, or sudden cardiac death. Seek immediate medical help if you experience symptoms like chest pain, difficulty breathing, or weakness.

• Risk of Misuse and Dependency: Being a controlled substance, testosterone gel can be misused, leading to serious heart and mental health issues. Use only as prescribed and avoid combining with other testosterone-containing medications.

• Prostate Health: Individuals with an enlarged prostate may experience worsening symptoms. Notify your healthcare provider if you notice changes in urination patterns.

• Liver Health: Although not directly linked to testosterone gel, certain testosterone forms can cause liver damage. Monitor for symptoms such as stomach pain or yellowing of the skin.

• Edema: The medication may lead to fluid retention, causing swelling in the arms and legs, especially if taken with corticosteroids or if you have heart, liver, or kidney issues.

• Sleep Apnea: Testosterone gel can exacerbate sleep apnea symptoms, particularly in those with obesity or lung disease. Discuss any changes in sleep patterns with your provider.

• High Calcium Levels: Patients with a history of cancer should be aware of the risk of high calcium levels in the blood. Regular monitoring is advised.

Contraindications include use in males with breast or prostate cancer, and women who are pregnant or breastfeeding should avoid this medication due to potential health risks. Always consult with your healthcare provider to ensure this medication is safe for you.

When taking this medication, you may experience some common side effects, which are usually mild and manageable. These include nausea, vomiting, headache, dizziness, hair loss, trouble sleeping, changes in sexual desire, acne, skin irritation, rash, itchiness, and changes in skin color. In some cases, there might be an increase in red blood cell count and enlarged prostate. If these symptoms persist or worsen, it's advisable to consult your healthcare provider.

More serious side effects, though less common, require prompt medical attention. These include breast enlargement, swelling of the feet or ankles, significant weight gain, difficulty breathing, weakness, urinary issues, and changes in mood such as depression or anxiety. Additionally, you might notice a change in testicle size or experience testicle pain, stomach pain, dark urine, yellowing of the eyes or skin, and irregular heartbeat. Diabetics should be aware of potential blood sugar changes, leading to symptoms like shakiness and rapid pulse.

In rare instances, severe side effects such as heart attack, stroke, or blood clots can occur. These manifest as chest pain, severe headaches, or sudden dizziness, among other symptoms. Immediate medical attention is crucial if these arise. Furthermore, liver damage signs include abdominal pain, nausea, and changes in skin color. Rare allergic reactions might present as rash, swelling, or trouble breathing, necessitating urgent care.

Lastly, males may experience a painful or prolonged erection lasting over four hours, which requires immediate medical intervention. Always report any side effects to your healthcare provider for appropriate guidance.