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When using this medication, it is vital to be aware of potential interactions and precautions to ensure safe usage. Below are the key considerations:

• Drug Interactions: Avoid combining this medication with certain MAO inhibitors, as this could lead to a severe and potentially life-threatening interaction. These inhibitors include isocarboxazid, metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, and tranylcypromine. It is generally advised not to use MAO inhibitors for at least two weeks before and after your treatment with this medication. Consult your doctor for guidance on when to begin or discontinue using this medication.

• Other Interacting Substances: Be cautious if using products such as skin-applied antihistamines (e.g., diphenhydramine cream, ointment, spray) and rolapitant alongside this medication. Additionally, inform your healthcare provider if you are taking any substances that might induce drowsiness. This includes opioid pain or cough medications (like codeine and hydrocodone), alcohol, marijuana (cannabis), sleep or anxiety medications (such as alprazolam, lorazepam, zolpidem), muscle relaxants (e.g., carisoprodol, cyclobenzaprine), or other antihistamines (such as cetirizine, diphenhydramine).

• Checking Medication Labels: Review labels on all medications, including those for allergies or cough-and-cold, as they may contain ingredients that could cause drowsiness. Consult your pharmacist on the safe use of these products.

• Medical and Laboratory Interference: This medication might affect certain medical or laboratory tests, such as brain scans for Parkinson's disease, urine drug screenings, and allergy skin tests, potentially leading to inaccurate results. Ensure that all healthcare professionals and lab personnel are informed that you are using this medication.

By adhering to these guidelines, you can help minimize risks and ensure the effective and safe use of your medication.

Avoid using certain MAO inhibitors with this medication, as this can lead to a serious, potentially life-threatening interaction. Specifically, do not use isocarboxazid, Metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, Rasagiline, safinamide, Selegiline, or Tranylcypromine while on this medication. Generally, MAO inhibitors should also be avoided for two weeks before and after treatment. Consult your healthcare provider for guidance on when to start or stop this medication.

Other interactions include skin-applied antihistamines (such as diphenhydramine cream, ointment, or spray) and rolapitant. Inform your doctor or pharmacist if you are using other substances that can cause drowsiness, such as opioid pain or cough medications (like codeine or Hydrocodone), alcohol, marijuana, sleep aids or anxiety medications (such as Alprazolam, Lorazepam, or Zolpidem), muscle relaxants (like Carisoprodol or Cyclobenzaprine), or additional antihistamines (such as Cetirizine or diphenhydramine).

Review all your medications, including those for allergies or cough and cold, as they may contain ingredients that cause drowsiness. Your pharmacist can help ensure you use these products safely.

Additionally, this medication may affect the results of certain medical or laboratory tests, including brain scans for Parkinson's disease, urine drug screenings, and allergy skin tests, potentially leading to false results. Be sure to inform lab personnel and all your healthcare providers that you are using this medication.