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When taking this medication, you might experience some common side effects such as drowsiness, dizziness, headaches, blurred vision, upset stomach, nausea, constipation, or a dry mouth, nose, or throat. These effects are usually mild and temporary. You can manage dry mouth by sucking on sugarless hard candy, chewing gum, drinking water, or using a saliva substitute. Staying hydrated is important to prevent mucus in your lungs from becoming thick and difficult to clear, but follow your healthcare provider's advice on fluid intake.

If you experience dizziness or lightheadedness, especially when standing up, try getting up slowly from sitting or lying positions. Most individuals using this medication do not encounter serious side effects. However, be aware of more serious reactions such as mental or mood changes, ringing in the ears, tremors, difficulty urinating, weakness, easy bruising or bleeding, irregular heartbeat, or seizures. If you notice any of these, inform your healthcare provider immediately.

Although rare, some people may have a severe allergic reaction. Seek immediate medical attention if you notice symptoms like a rash, itching or swelling of the face, tongue, or throat, severe dizziness, or trouble breathing. If you observe other side effects not mentioned here, contact your healthcare provider for guidance. Remember, the occurrence of serious side effects is uncommon, but it is important to stay informed and vigilant.

Avoid using certain MAO inhibitors with this medication, as this can lead to a serious, potentially life-threatening interaction. Specifically, do not use isocarboxazid, Metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, Rasagiline, safinamide, Selegiline, or Tranylcypromine while on this medication. Generally, MAO inhibitors should also be avoided for two weeks before and after treatment. Consult your healthcare provider for guidance on when to start or stop this medication.

Other interactions include skin-applied antihistamines (such as diphenhydramine cream, ointment, or spray) and rolapitant. Inform your doctor or pharmacist if you are using other substances that can cause drowsiness, such as opioid pain or cough medications (like codeine or Hydrocodone), alcohol, marijuana, sleep aids or anxiety medications (such as Alprazolam, Lorazepam, or Zolpidem), muscle relaxants (like Carisoprodol or Cyclobenzaprine), or additional antihistamines (such as Cetirizine or diphenhydramine).

Review all your medications, including those for allergies or cough and cold, as they may contain ingredients that cause drowsiness. Your pharmacist can help ensure you use these products safely.

Additionally, this medication may affect the results of certain medical or laboratory tests, including brain scans for Parkinson's disease, urine drug screenings, and allergy skin tests, potentially leading to false results. Be sure to inform lab personnel and all your healthcare providers that you are using this medication.