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When taking this medication, it is important to be aware of potential interactions and precautions to ensure safety and effectiveness. Here are some key points to consider:

• Drug Interactions: Certain medications, such as burosumab and phosphate binders, may interact with this drug. Therefore, it is crucial to consult with your healthcare provider before combining them.

• Product Labels: Be vigilant about checking the labels of all your prescription and over-the-counter medications, including herbal products. Some of these may contain calcium, magnesium, phosphate, or vitamin D, which could affect how this drug works. Your pharmacist is a valuable resource for guidance on safely using these products.

• Avoid Certain Medications: Since vitamin D is very similar to calcitriol, it is advised not to use medications containing calcitriol concurrently with vitamin D.

• Laboratory Tests: This vitamin may affect the results of certain laboratory tests, such as cholesterol tests, potentially leading to inaccurate results. Inform all your healthcare providers and lab personnel about your use of this vitamin to avoid misinterpretations.

Follow these instructions carefully, and consult with your healthcare provider for personalized advice tailored to your specific health needs.

Less common but important to monitor:

• Nausea
• Vomiting
• Constipation
• Loss of appetite
• Increased thirst
• Frequent urination
• Mood changes
• Unusual fatigue

Serious side effects:

• Rash
• Itching
• Swelling of the face, tongue, or throat
• Severe dizziness
• Difficulty breathing

Interactions with high risk of serious adverse effects and should be avoided:

• Calcitriol

Interactions with moderate risk that may require dose adjustment, closer monitoring, or timing changes:

• burosumab
• phosphate binders