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Vitamin D, available as ergocalciferol-D2, cholecalciferol-D3, and alfacalcidol, is a vital fat-soluble vitamin that aids in the absorption of calcium and phosphorus, essential for maintaining strong bones. It is primarily used to treat and prevent bone-related conditions like rickets and osteomalacia. The body produces Vitamin D when the skin is exposed to sunlight. However, factors such as sunscreen use, protective clothing, limited sun exposure, darker skin, and aging can hinder adequate Vitamin D synthesis from sunlight. Therefore, Vitamin D, often combined with calcium, is crucial in treating or preventing osteoporosis. Additionally, it supports the treatment of low calcium or phosphate levels due to certain conditions like hypoparathyroidism, pseudohypoparathyroidism, and familial hypophosphatemia. For those with kidney disease, it helps maintain normal calcium levels and supports proper bone growth. Due to typically low Vitamin D levels in breast milk, supplements are recommended for breastfed infants to ensure proper growth and development.