
Diosmin Coupons & Savings Card – Discount Prices from $72.52
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1GM, Diosmin (1 Bottle)
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CVS
$104.75
COUPON PRICE
Walmart
$72.52
COUPON PRICE
Walgreens
$83.51
COUPON PRICE
Albertsons
$92.04
COUPON PRICEDiosmin savings card
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Walmart
$72.52
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PCN
GRP
019876
LH9D26972E
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Diosmin dosage forms
Dosage Quantity Price from Per unit 1GM 1 Bottle $72.52 $72.52 1GM 2 Bottles $164.03 $82.02 1GM 3 Bottles $255.54 $85.18
| Dosage | Quantity | Price from | Per unit |
|---|---|---|---|
| 1GM | 1 Bottle | $72.52 | $72.52 |
| 1GM | 2 Bottles | $164.03 | $82.02 |
| 1GM | 3 Bottles | $255.54 | $85.18 |
Diosmin Warnings
Diosmin Side Effects
Diosmin Interactions
Diosmin, a flavonoid commonly used to treat conditions like hemorrhoids and chronic venous insufficiency, can interact with various medications, potentially altering their effectiveness or increasing the risk of adverse effects. Notably, diosmin may influence the body's processing of certain drugs by affecting liver enzymes and drug transport proteins.
One significant interaction involves anticoagulant and antiplatelet medications, such as Warfarin, Clopidogrel, and Aspirin. Combining diosmin with these drugs may heighten the risk of bleeding. For instance, there has been a reported case where a 77-year-old woman experienced spontaneous intraventricular hemorrhage after prolonged use of diosmin alongside warfarin and aspirin, despite having an international normalized ratio (INR) of only 1.8. Experts suggest that chronic intake of diosmin may predispose individuals to bleeding complications by affecting blood vessel function and inhibiting platelet aggregation.
Diosmin may also interact with medications metabolized by specific liver enzymes, particularly those in the cytochrome P450 family. By inhibiting these enzymes, diosmin can slow the breakdown of certain drugs, leading to increased blood levels and a higher risk of side effects. Medications potentially affected include:
Nonsteroidal anti-inflammatory drugs (NSAIDs): Such as Diclofenac and Ibuprofen.
Anticonvulsants: Including Carbamazepine and Phenytoin.
Muscle relaxants: Like Chlorzoxazone.
Additionally, diosmin may inhibit P-glycoprotein, a protein that helps transport certain drugs out of cells. This inhibition can lead to increased absorption and higher blood levels of P-glycoprotein substrates, such as the antihistamine Fexofenadine. A study involving healthy volunteers found that co-administration of diosmin significantly increased the peak plasma concentration and overall exposure of fexofenadine, suggesting a potential for enhanced effects and side effects.
Given these interactions, it's crucial to inform your healthcare provider about all medications and supplements you are taking before starting diosmin. This will help ensure safe and effective use of diosmin while minimizing the risk of adverse interactions.
