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Doxazosin

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Doxazosin is used alone or with other drugs to treat high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. This medication works by relaxing blood vessels so blood can flow more easily. Doxazosin is also used in men to treat the symptoms of an enlarged prostate (benign prostatic hyperplasia-BPH). It does not shrink the prostate, but it works by relaxing the muscles in the prostate and part of the bladder. This helps to relieve symptoms of BPH such as difficulty in beginning the flow of urine, weak stream, and the need to urinate often or urgently (including during the middle of the night). Doxazosin belongs to a class of drugs known as alpha blockers.
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Doxazosin Side Effects

Dizziness, lightheadedness, drowsiness, unusual tiredness, or weight gain may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor right away if you have any serious side effects, including: signs of infection (such as sore throat that doesn't go away, fever), fainting, shortness of breath, weakness, swelling of hands/feet. Get medical help right away if you have any very serious side effects, including: chest pain. Rarely, males may have a painful or prolonged erection lasting 4 or more hours. If this occurs, stop using this drug and get medical help right away, or permanent problems could occur. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Interactions

Some products that may interact with this drug include: other alpha blocker drugs (such as prazosin, tamsulosin). If you are also taking a drug to treat erectile dysfunction-ED or pulmonary hypertension (such as sildenafil, tadalafil), your blood pressure may get too low which can lead to dizziness or fainting. Your doctor may need to adjust your medications to minimize this risk. Other medications can affect the removal of doxazosin from your body, which may affect how doxazosin works. Examples include azole antifungals (such as itraconazole, ketoconazole), macrolide antibiotics (such as clarithromycin), HIV protease inhibitors (such as lopinavir), ritonavir, among others. Some products have ingredients that could raise your blood pressure. Tell your pharmacist what products you are using, and ask how to use them safely (especially cough-and-cold products, diet aids, or NSAIDs such as ibuprofen/naproxen).
Doxazosin FAQs
What is the drug doxazosin used for?

Doxazosin is used to treat high blood pressure (hypertension) and symptoms of benign prostatic hyperplasia (BPH), which is an enlarged prostate. It works by relaxing blood vessels so blood can flow more easily and by relaxing muscles in the prostate and bladder neck, making it easier to urinate.

Alpha blockers are not typically used as a primary treatment for erectile dysfunction (ED). They are primarily used to treat conditions like high blood pressure and benign prostatic hyperplasia (BPH). However, some alpha blockers, such as Tamsulosin, may have a secondary effect of improving ED symptoms in some men, particularly those with BPH. It is important for individuals to consult with a healthcare provider to determine the most appropriate treatment for ED based on their specific health needs and conditions.

The most common side effect of doxazosin is dizziness, particularly when standing up quickly, due to its blood pressure-lowering effects.

It is generally advised to exercise caution when taking Viagra (sildenafil) with doxazosin. Both medications can lower blood pressure, and taking them together may increase the risk of hypotension (low blood pressure), dizziness, or fainting. It is important to consult with a healthcare provider before combining these medications to ensure it is safe based on the individual's health condition and other medications they may be taking.

Yes, doxazosin can increase urination. It is often used to treat symptoms of an enlarged prostate, such as difficulty urinating, by relaxing the muscles in the bladder and prostate, which can lead to increased urine flow.

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