Droxidopa

Drug Details

Droxidopa, also known as Northera, is prescribed for adults experiencing neurogenic orthostatic hypotension (nOH), a condition characterized by low blood pressure when standing, often due to specific neurological disorders like multiple system atrophy, pure autonomic failure, or Parkinson's disease. This medication is particularly beneficial for individuals whose daily activities are significantly impaired by nOH, even after other treatments, such as support stockings or increased fluid intake, have been tried. Droxidopa functions by converting into norepinephrine in the body, a hormone that constricts blood vessels, thereby elevating blood pressure. This process helps alleviate symptoms such as dizziness, lightheadedness, or a sensation of imminent fainting. The medication is typically taken orally three times a day, with the last dose administered at least three hours before bedtime to minimize the risk of elevated blood pressure while lying down, which can lead to serious complications like heart issues or stroke. Users may experience side effects such as headaches and dizziness. As with any medication, it is crucial to consult with a healthcare provider before starting droxidopa to ensure it is appropriate and safe based on individual health needs.