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This medication can increase your blood pressure when you are lying on your back (supine hypertension). Raising the head of the your bed lessens this risk. Your doctor will carefully monitor your blood pressure in this position before and during treatment, especially after a dosage increase. Your doctor may adjust or stop treatment with this medication if supine hypertension happens and cannot be managed by raising the head of your bed. If supine hypertension cannot be managed, it could lead to a stroke, heart attack, or even death. Talk with your doctor for details.

Headache, nausea, or dizziness may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. This medication can increase your blood pressure, especially when you are lying down (supine hypertension). Monitor and share your blood pressure results with your doctor. Tell your doctor if you have symptoms of high blood pressure, such as pounding heartbeat, pounding sound in your ears, headache, or blurred vision. This medication may rarely cause very serious symptoms that are like a condition called neuroleptic malignant syndrome (NMS). These symptoms may be more likely to happen when your dose of this drug or other medications (such as levodopa) is changed. Get medical help right away if you have any of the following symptoms: fever, muscle stiffness, severe confusion, sweating, fast/irregular heartbeat. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.