Fibrates: Uses, Common Brands, and Safety Info

Fibrates are medications used for conditions related to high triglyceride levels and low HDL cholesterol. They help lower triglycerides and increase HDL cholesterol. Common brands include Tricor, Lopid, and Bezalip. Fibrates should be used with caution if there are liver or kidney issues, gallbladder disease, or a history of pancreatitis. Side effects may include stomach discomfort, diarrhea, nausea, or muscle pain. Working with a healthcare provider is important for


Fibrates are a class of medications commonly used to treat conditions related to elevated levels of triglycerides and low levels of high-density lipoprotein (HDL) cholesterol. They work by affecting the body's lipid metabolism, helping to decrease triglyceride levels and increase HDL cholesterol levels.


Fibrates are primarily prescribed to individuals with high levels of triglycerides, a type of fat found in the blood. High triglyceride levels can increase the risk of developing cardiovascular diseases, such as heart attack or stroke. Fibrates can help reduce the risk of these conditions by lowering triglyceride levels. Additionally, fibrates may be used in combination with other cholesterol-lowering medications, such as statins, to manage mixed dyslipidemia—when both elevated triglycerides and low HDL cholesterol are present.

Common Brands

There are several common brand names for fibrates available on the market. Some of these include:

  • Fenofibrate (Tricor)

  • Gemfibrozil (Lopid)

  • Bezafibrate (Bezalip)

It is essential to consult with a healthcare professional to determine the most appropriate brand and dosage for an individual's specific condition.


While fibrates are generally considered safe and effective, they may not be suitable for everyone. Individuals with liver or kidney disease, gallbladder disease, or a history of pancreatitis should exercise caution when using fibrates. Furthermore, fibrates may interact with other medications, such as warfarin or statins, so it is crucial to inform the healthcare provider about any other medications being taken.

Like any medication, fibrates can have side effects. Some common side effects include stomach discomfort, diarrhea, nausea, or muscle pain. If any severe side effects or allergic reactions occur, such as difficulty breathing or swelling, immediate medical attention should be sought.

Overall, fibrates can be an effective treatment option for individuals with high triglyceride levels or mixed dyslipidemia. However, it is essential to work closely with a healthcare provider to ensure the medication is appropriate and monitored for efficacy and safety.