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It is crucial to be informed about the safety and warning details related to the use of this medication. Please review the following points carefully and consult your healthcare provider if you have any questions or concerns.

• Smoking and Cardiovascular Risks: If you are a female over the age of 35 and smoke cigarettes, using hormonal birth control, such as combined oral contraceptives (COCs), significantly increases the risk of serious cardiovascular issues, including stroke, heart attack, and blood clots. You are advised to explore alternative birth control options with your healthcare provider.

• Blood Clot Risks: The use of Quartette may increase the risk of blood clots, which can occur in various parts of the body such as the lungs, legs, brain, and heart. This risk is higher for females over 35 who smoke, those who have recently undergone surgery, or those who have high blood pressure, obesity, high cholesterol, or diabetes. Immediate medical attention is required if signs of blood clots appear.

• Irregular Bleeding: Some users of Quartette may experience spotting or irregular bleeding, especially during the initial three months of use. This is usually temporary, but if it becomes problematic, consult your healthcare provider. If you miss a period, a pregnancy test is recommended.

• High Blood Pressure: Quartette may elevate blood pressure, particularly in older females or those who have been on birth control for an extended period. Regular monitoring of blood pressure is advised. It is contraindicated in individuals with uncontrolled high blood pressure.

• Blood Sugar and Cholesterol: Quartette can increase blood sugar and cholesterol levels. This is particularly concerning for individuals with pre-existing diabetes, prediabetes, or high triglycerides, as it may lead to pancreatitis. Regular monitoring is recommended when using this medication.

• Headaches: Report any new or worsening headaches or migraines to your healthcare provider. Persistent or severe headaches may require discontinuation of the medication.

• Cancer Risks: There is a potential risk of breast and cervical cancer with prolonged use of COCs, including Quartette. Those with a history of breast cancer should exercise caution.

• Liver Concerns: Although rare, Quartette can cause liver issues, including damage or tumors. Do not use this medication if you have existing liver problems and seek immediate medical advice if symptoms of liver issues occur.

• Drug Interactions: Inform your healthcare provider about all medications you are taking. Certain drugs can reduce the effectiveness of Quartette, increasing the risk of pregnancy, or can enhance side effects.

• Contraindications: Quartette should not be used by females over 35 who smoke, those with a history of blood clots, heart attacks, strokes, uncontrolled high blood pressure, severe migraines, liver issues, unexplained vaginal bleeding, pregnancy, or a history of breast cancer. It is also contraindicated for those taking certain hepatitis C medications.

Please consult with your healthcare provider to ensure this medication is safe for you, considering your personal health conditions and any other medications you may be taking.

When taking this medication, you may experience some mild side effects, such as nausea, vomiting, headaches, and breast tenderness. Fluid retention can lead to swelling in the ankles or feet, and there may be changes in weight. It's common to have vaginal bleeding between periods, especially in the initial months of usage, and this is generally not a cause for concern. Acne and menstrual cramps are also reported by some users. If these effects persist or worsen, consult your healthcare provider.

There are more serious side effects associated with this medication that require your attention. Mood changes, anxiety attacks, and migraines are possible and should be discussed with your healthcare provider if they occur. A rise in blood pressure is another consideration, so regular monitoring is advisable. Rare but severe side effects include lumps in the breast, severe abdominal pain, and unusual changes in vaginal bleeding, such as continuous spotting or sudden heavy bleeding.

This medication can, though rarely, lead to significant complications like blood clots, which can result in heart attacks, strokes, deep vein thrombosis, or pulmonary embolism. Symptoms such as chest pain, sudden dizziness, or trouble breathing require immediate medical attention. Liver issues may present as jaundice, fatigue, or dark urine. In very rare cases, there might be symptoms of an ectopic pregnancy or suicidal thoughts, both of which necessitate urgent care.

While allergic reactions are infrequent, they can be serious. Seek immediate help if you experience symptoms like rash, swelling, severe dizziness, or difficulty breathing. Always communicate with your healthcare provider about any unusual symptoms or side effects you encounter.