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Please be informed of the following crucial safety and warning information regarding the use of this medication. It is essential to carefully review these details and consult your healthcare provider if you have any questions or concerns.

• Digestive Tract Blockage: There is a potential risk that Lanthanum (Fosrenol) may cause blockages in the stomach, intestines, or rectum, which can be dangerous. This risk is increased for individuals with a history of anatomical changes in the digestive tract, persistent constipation issues, or those taking other medications that can lead to blockages. Immediate medical attention is advised if you experience severe constipation, intense abdominal pain, or pronounced bloating.

• X-ray Interference: Lanthanum (Fosrenol) may be visible on abdominal X-rays. It is important to notify your healthcare provider or the radiology technician prior to undergoing an X-ray, as the presence of lanthanum (Fosrenol) can affect the results.

There are no known contraindications associated with this medication. Always follow the guidance of your healthcare provider and report any unusual symptoms or concerns promptly.

When taking this medication, you might experience some common side effects, including nausea, vomiting, stomach pain, diarrhea, or constipation. These effects are usually mild and often temporary. However, if they continue or worsen, it's important to consult your healthcare provider.

In rare instances, more serious side effects may occur. Be vigilant for any mental or mood changes, unusual muscle weakness or spasms, or seizures, and seek medical attention if these symptoms arise. Additionally, though uncommon, a severe blockage or perforation of the bowels could develop, which might necessitate hospital care or surgery. Symptoms to watch for include persistent or severe abdominal pain, unstoppable vomiting, severe constipation or diarrhea, fever, and chills.

Allergic reactions to this medication are very rare but can be severe. If you notice a rash, itching or swelling, particularly of the face, tongue, or throat, experience severe dizziness, or have trouble breathing, seek immediate medical help. Always be attentive to any side effects not listed here and discuss them with your healthcare provider.

Lanthanum, known as Fosrenol, can affect the effectiveness of certain medications if taken simultaneously. It's important to inform your doctor and pharmacist about all the medications and supplements you are currently using, whether they are prescription, over-the-counter, or herbal.

To avoid interactions, you may need to take lanthanum at least two hours apart from specific medicines, including mycophenolate, thyroid medications like levothyroxine, and tetracycline antibiotics such as doxycycline and tetracycline. Additionally, consult your healthcare provider for specific timing when taking quinolone antibiotics, such as ciprofloxacin and levofloxacin, as they may require different scheduling.

There are other medications, like erdafitinib, that are usually not recommended to be taken with lanthanum unless necessary. If prescribed together, your doctor might adjust the dosage or frequency. For some medicines, including a range of antibiotics and other drugs like levothyroxine and mycophenolate mofetil, using them with lanthanum could increase the risk of side effects, though it may be the best treatment option in certain situations. Your doctor will guide you on how to properly manage these interactions.