Drowsiness, dizziness, headache, nausea, vomiting, loss of appetite, constipation, stomach upset, blurred vision, decreased coordination, and dry mouth/nose/throat may occur. These effects may decrease as your body adjusts to the medication. If any of these effects last or get worse, contact your doctor or pharmacist promptly. To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. To relieve dry mouth, suck (sugarless) hard candy or ice chips, chew (sugarless) gum, drink water, or use a saliva substitute. Triprolidine can dry up and thicken mucus in your lungs, making it more difficult to breathe and clear your lungs. To help prevent this effect, drink plenty of fluids unless otherwise directed by your doctor. If your doctor has directed you to use this medication, remember that your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor right away if you have any serious side effects, including: mental/mood changes (such as hallucinations, irritability, nervousness), ringing in the ears, trouble urinating, easy bruising/bleeding, fast/irregular heartbeat, seizures. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Avoid using this medication with skin-applied antihistamines, such as diphenhydramine creams, ointments, or sprays, as it may increase side effects. Inform your doctor or pharmacist if you are taking other substances that can cause drowsiness, including opioid painkillers or cough suppressants like codeine and hydrocodone, alcohol, marijuana, sleep aids or anxiety medications like alprazolam, lorazepam, or zolpidem, muscle relaxants such as carisoprodol and cyclobenzaprine, or any other antihistamines like cetirizine or diphenhydramine. Be sure to check all your medications, including those for allergies or cold symptoms, as they might contain ingredients that cause drowsiness. Consult your pharmacist to safely use these products. Additionally, this medication might affect certain laboratory tests, such as allergy skin tests, leading to inaccurate results. Ensure that your healthcare providers and lab personnel are aware that you are using this medication.