Inspirease

Drug Details

The Inspire Upper Airway Stimulation (UAS) system is an implantable device designed to treat moderate to severe obstructive sleep apnea (OSA) in adults who cannot tolerate or do not benefit from continuous positive airway pressure (CPAP) therapy. The system consists of three main components: a neurostimulator implanted in the chest, a stimulation lead connected to the hypoglossal nerve, and a sensing lead that monitors breathing patterns. During sleep, the device delivers mild electrical impulses to the hypoglossal nerve, causing the tongue to move forward and keeping the airway open. Patients control the device using a handheld remote, turning it on before sleep and off upon waking. Clinical studies have demonstrated significant reductions in sleep apnea severity and improvements in quality of life for patients using the Inspire system. However, potential side effects may include discomfort from stimulation, tongue soreness, and dry mouth. The device is not suitable for individuals with complete blockage of the upper airway or certain other medical conditions.