Lithium

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Lithium is a medication used to manage bipolar disorder, specifically targeting manic episodes and providing long-term stability. It functions as a mood stabilizer by restoring balance to certain brain chemicals that regulate mood, although the exact mechanism is not fully understood. The primary benefits of lithium include reducing the frequency and severity of manic episodes, which can manifest as extreme mood swings, irritability, anxiety, rapid speech, and aggressive behavior. Lithium is available in various forms, including instant-release pills, oral liquid, and extended-release tablets. It's typically taken two to three times daily. While effective, lithium can cause side effects such as shakiness, thirst, and nausea. Regular monitoring of blood lithium levels is necessary to ensure a safe dosage and prevent toxicity. For accurate medical advice and to tailor treatment to your needs, it is essential to consult healthcare professionals like doctors, nurses, or pharmacists. They can provide guidance on the safe and effective use of lithium and other medications.
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473ML of 8MEQ/5ML, Lithium (1 Bottle)

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CVS

$100.77

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Walgreens

$77.74

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Albertsons

$86.17

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Rite Aid

$227.95

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$240.36

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CVS

$100.77

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Lithium dosage forms

The average cost for 1 Bottle of Lithium at 473ML of 8MEQ/5ML is $77.74 with a free coupon. This is 9.63% off the average retail price of $806.97
DosageQuantityPrice fromPer unit
473ML of 8MEQ/5ML1 Bottle$77.74$77.74

Lithium Warnings

Lithium is a medication that requires careful monitoring due to the potential risks associated with its use. It is crucial to maintain appropriate levels of lithium in your body. An excess can lead to severe side effects, and thus, regular medical supervision is essential during treatment. Below are important safety considerations to keep in mind when using lithium:

  • Lithium Toxicity: High levels of lithium in the blood can cause toxicity, leading to symptoms such as nausea, diarrhea, vomiting, shaking, muscle weakness, confusion, and trouble breathing. It is vital to have your lithium levels checked regularly by your healthcare provider, and any symptoms of toxicity should be reported immediately.

  • Kidney Health: Lithium can affect kidney function and the body's ability to balance salt and water. Monitor for signs like frequent urination, increased thirst, bloody or foamy urine, lower back pain, and fatigue. Consistent fluid and salt intake is important, and any indication of kidney damage should be addressed with your healthcare provider.

  • Serotonin Syndrome: This rare but serious condition can occur when lithium is taken with other medications that increase serotonin levels. Symptoms include a fast heart rate, sweating, muscle stiffness, fever, and confusion. It is essential to inform your provider about all medications you are taking.

  • Thyroid Issues: Lithium may cause thyroid problems, such as hypothyroidism or hyperthyroidism. Symptoms include tiredness, weight changes, and temperature sensitivity. Regular monitoring of thyroid function is recommended.

  • Heart Problems (Brugada Syndrome): Lithium can exacerbate Brugada syndrome, a rare heart rhythm disorder. Those with a personal or family history of this condition should consult a cardiologist before starting lithium.

  • Low Blood Sodium Levels: Lithium may lead to low sodium levels in the blood, a condition that requires immediate medical attention if symptoms such as weakness, confusion, or headaches occur.

  • High Blood Calcium and Parathyroid Hormone Levels: Long-term lithium use can increase calcium levels in the blood. Symptoms include tiredness, muscle weakness, and digestive issues. Monitoring of calcium and parathyroid hormone levels is important.

  • Brain-related Side Effects: Combining lithium with antipsychotic medications may increase the risk of neurological side effects like tremors and confusion. Immediate medical attention is advised if these occur.

Contraindications:

  • Do not use lithium if you are allergic to any lithium-containing products. Consult your healthcare provider if you have any concerns or if you suspect an allergy.

Regular communication with your healthcare provider and adherence to prescribed monitoring schedules are essential for safe lithium use.

Lithium Side Effects

Common side effects:

  • drowsiness
  • dizziness
  • tiredness
  • increased thirst
  • increased frequency of urination
  • weight gain
  • mild hand tremors
  • general discomfort

Less common but important to monitor:

  • nausea or vomiting
  • urinating more frequently
  • tremors
  • tiredness
  • dizziness
  • changes in thyroid hormone levels

Serious side effects:

  • severe dizziness
  • fainting
  • irregular heartbeat
  • shortness of breath
  • seizures
  • severe tremors
  • serotonin syndrome/toxicity
  • rapid heartbeat
  • hallucinations
  • loss of coordination
  • severe nausea, vomiting, diarrhea
  • muscle twitching
  • unexplained fever
  • unusual agitation
  • allergic reactions
  • swollen lymph nodes
  • rash
  • severe itching or swelling
  • difficulty breathing

Lithium Interactions

Interactions with high risk of serious adverse effects and should be avoided:

  • MDMA
  • St. John's Wort
  • Fluoxetine
  • Paroxetine
  • Duloxetine
  • Venlafaxine

Interactions with moderate risk that may require dose adjustment, closer monitoring, or timing changes:

  • Captopril
  • Enalapril
  • Losartan
  • Valsartan
  • Celecoxib
  • Ibuprofen
  • Hydrochlorothiazide
  • Furosemide
  • Chlorpromazine
  • Haloperidol
Lithium FAQs
What is the drug lithium used for?

Lithium is primarily used to treat and manage bipolar disorder. It helps to stabilize mood and reduce the severity and frequency of manic and depressive episodes. It may also be used to treat other mood disorders as determined by a healthcare provider.

Doctors still prescribe lithium, particularly for the treatment of bipolar disorder. However, its use may be less frequent due to the availability of newer medications with fewer side effects. Lithium requires regular monitoring of blood levels to avoid toxicity, and it can have significant side effects, which may lead some doctors to consider alternative treatments. Nonetheless, lithium remains an effective option for many patients.

Lithium primarily affects the central nervous system by stabilizing mood and reducing the severity and frequency of mood swings. It is commonly used to treat bipolar disorder. Lithium works by influencing the flow of sodium through nerve and muscle cells, which affects excitation or mania. It also helps to balance neurotransmitters in the brain, such as serotonin and dopamine, contributing to mood stabilization. Regular monitoring of blood levels is necessary to ensure therapeutic effectiveness and prevent toxicity.

The biggest side effect of lithium is its potential to affect kidney function, leading to nephrotoxicity. It can also cause thyroid dysfunction, particularly hypothyroidism. Regular monitoring of kidney and thyroid function is recommended for individuals taking lithium.

The three main symptoms of lithium toxicity are nausea and vomiting, tremors, and confusion.