Eplerenone

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eplerenone

Eplerenone, also known by the brand name Inspra, is a medication used to manage high blood pressure and improve survival rates in individuals with heart failure after a heart attack. It is available in tablet form and can be taken alone or alongside other medications. Eplerenone functions as a mineralocorticoid receptor antagonist by blocking the hormone aldosterone. This action reduces the amount of sodium and water retained in the body, effectively lowering blood pressure. By controlling high blood pressure, eplerenone helps prevent serious complications such as strokes, heart attacks, and kidney problems. Always consult with your healthcare provider before starting any new medication.
Our Inspra coupons are free to use. You can print the coupon, email it to yourself, or receive the Inspra coupon via text message. To get your free discount, show the pharmacist your Inspra savings card which has the discounted coupon price. Use our filters below to edit the prescription box to match your needs. The Inspra prices will update based on your prescription needs. Above our Inspra coupons, you can change the location to see pharmacy prices in other areas. Our prescription discount card will update online with the specific pharmacy costs associated with your edits. Be sure to text, email, or print the Inspra savings card code that you need after editing the prescription box and location field. Show the discount card to your pharmacist before paying.

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25MG, Eplerenone (30 Tablets)

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CVS

$23.70

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$16.60

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$18.45

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$26.94

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$31.85

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$23.70

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Inspra dosage forms

The average cost for 30 Tablets of Inspra (eplerenone) at 25MG is $16.6 with a free coupon. This is 13.27% off the average retail price of $125.1
DosageQuantityPrice fromPer unit
25MG30 Tablets$16.6$0.55
50MG30 Tablets$21.1$0.7

Inspra Warnings

This safety information provides crucial details about the potential risks and necessary precautions associated with the use of this medication. Please read thoroughly and discuss any concerns with your healthcare provider.

  • Risk of High Potassium Levels (Hyperkalemia): The use of Eplerenone (Inspra) may lead to elevated potassium levels in the blood, which can be dangerous. Extremely high potassium levels can affect heart rhythm and, in severe cases, lead to cardiac arrest. Individuals with existing kidney issues, diabetes, or those taking medications such as ACE inhibitors, ARBs, and NSAIDs are at an increased risk. Be vigilant for symptoms like sudden numbness, tingling, nausea, or muscle weakness. Contact your healthcare provider immediately if these occur, as they may need to adjust your dosage.

  • Contraindications: This medication is not suitable for everyone. It should be avoided by individuals with:

    • Critically high potassium levels.
    • Severe kidney issues.
    • Concurrent use of specific medications, including ketoconazole, ritonavir (Norvir), or clarithromycin.
  • Specific Conditions:

    • For individuals with high blood pressure, avoid using this medication if you have type 2 diabetes with significant protein in the urine (microalbuminuria), moderate to severe kidney problems, or are using potassium supplements or potassium-sparing diuretics such as spironolactone (Aldactone), amiloride (Midamor), or triamterene (Dyrenium).

These guidelines are in place to ensure your safety while using this medication. Always consult your healthcare provider for personalized advice and before making any changes to your medication regimen.

Inspra Side Effects

When taking this medication, some common side effects may include headache, dizziness, digestive system issues, urinary tract problems, and shortness of breath. These are generally mild, but if they persist or worsen, it's important to contact your healthcare provider for advice. Some individuals may also experience skin issues, mental health changes, or a cough.

More serious side effects, though less common, should be addressed promptly. These include abnormal vaginal bleeding, enlargement or soreness of breasts in males, and symptoms associated with high potassium levels, such as muscle weakness and irregular heartbeat. Immediate medical attention is necessary for severe symptoms like chest pain or a heart attack.

While a severe allergic reaction is rare, be vigilant for symptoms such as rash, severe dizziness, or trouble breathing, and seek emergency medical help if these occur. Always communicate any unusual or severe side effects to your healthcare provider to ensure your safety and well-being.

Inspra Interactions

When taking Eplerenone (Inspra), it's important to be aware of potential interactions with other medications or supplements. Inform your healthcare provider about all the drugs and supplements you are currently using, including prescription, over-the-counter, vitamins, and herbal products.

Certain medications like those that increase potassium levels in the blood, such as birth control pills with drospirenone and potassium-sparing diuretics (e.g., amiloride, spironolactone, triamterene), may interact with Eplerenone. Additionally, lithium can also interact with this medication.

Some drugs can influence how Eplerenone is eliminated from your body, potentially altering its effectiveness. These include adagrasib, azole antifungals like ketoconazole and itraconazole, clarithromycin, cobicistat, nefazodone, certain HIV protease inhibitors like nelfinavir and ritonavir, and herbal supplements such as St. John's wort.

Moreover, certain products, especially those used for cough and cold, diet aids, or NSAIDs like ibuprofen and naproxen, may increase blood pressure or worsen heart failure. It’s crucial to discuss any such products with your pharmacist to ensure safe usage.

In some cases, using Eplerenone with other medications might not be advised or might require dose adjustments, such as with aceclofenac, aspirin, celecoxib, fluconazole, and many others. These interactions might increase side effects or affect treatment efficacy, so your healthcare provider may need to adjust dosages or monitor your treatment closely.

Inspra FAQs
What is the drug Inspra used for?

Inspra, also known by its generic name eplerenone, is used to treat high blood pressure (hypertension) and heart failure, particularly after a heart attack. It works by blocking the action of a hormone called aldosterone, which helps lower blood pressure and reduce the risk of heart-related complications.

Inspra is not a beta blocker. It is an aldosterone antagonist, also known as a mineralocorticoid receptor antagonist.

When taking eplerenone, it is advisable to avoid foods high in potassium. This includes bananas, oranges, tomatoes, potatoes, and spinach, as eplerenone can increase potassium levels in the blood. Additionally, it is recommended to avoid salt substitutes that contain potassium. Always consult with a healthcare provider for personalized dietary advice.

A major adverse effect of eplerenone is hyperkalemia, which is an elevated level of potassium in the blood. This condition can be serious and requires monitoring, especially in patients with impaired kidney function or those taking other medications that increase potassium levels.

Inspra is a medication known as an aldosterone antagonist. It is primarily used to treat high blood pressure and heart failure by blocking the effects of aldosterone, a hormone that can contribute to cardiovascular issues.