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It is essential to understand and adhere to the following safety information and warnings regarding the use of Levemir (insulin detemir). This will help ensure your well-being while using this medication. Should you have any concerns, please consult your healthcare provider promptly.

• Infection Risks: Do not share Levemir pens, syringes, or needles with others, as this could result in the transmission of serious infections.

• Low Blood Sugar (Hypoglycemia): Low blood sugar is a frequent side effect of insulin use, including Levemir. Symptoms such as shakiness, anxiety, confusion, or hunger indicate low blood sugar. If you experience these, check your blood sugar levels immediately. Always carry glucose tablets or other fast-acting sugars and use the "15-15 Rule" to stabilize your blood sugar. Consult your doctor if you have frequent episodes, as your insulin dose may need adjustment. Factors that increase risk include dietary and exercise changes, alcohol consumption, other blood sugar medications, age over 65, and liver or kidney issues.

• Severe Allergic Reactions: Though rare, Levemir may cause life-threatening allergic reactions. Seek emergency medical attention if you experience breathing difficulties, a rapid heartbeat, or swelling of the face, mouth, or throat.

• Low Blood Potassium Levels: Levemir can reduce potassium levels in your blood, which may be dangerous. You are at higher risk if you are on medications that lower potassium. Your doctor will monitor your potassium levels and may prescribe medications to maintain them. Notify your healthcare provider immediately if you encounter symptoms like muscle weakness, fatigue, a rapid heartbeat, or tingling in your extremities.

• Fluid Retention and Heart Failure Risk: If you are taking thiazolidinediones (TZD) for blood sugar control, inform your healthcare provider before starting Levemir. The combination can cause fluid retention, potentially worsening or leading to heart failure. Alert your provider if you experience sudden weight gain or heart failure symptoms like shortness of breath, fatigue, or headaches. Medication adjustments may be necessary.

Contraindications: Do not use this medication if you have untreated low blood sugars, as it can pose severe health risks. Always consult your healthcare provider if you have concerns or questions about these conditions.

When taking this medication, some individuals may experience common side effects that are generally mild. These include symptoms of low blood sugar such as shakiness and hunger, which can occur in up to 93% of users, depending on other medications taken for blood sugar. Other common effects are cold symptoms affecting the nose, throat, and lungs (up to 27%), headaches (up to 23%), throat pain or irritation (10%), back pain (8%), flu-like symptoms including fever and chills (up to 8%), and stomach pain (6%). While these side effects are usually not serious, consult your healthcare provider if they persist or worsen.

Additionally, some individuals may report other side effects like weight gain, swelling in the hands or feet due to fluid retention, and reactions at the injection site such as redness, pain, or itching. If these side effects are significant, contacting your healthcare provider is advisable.

There are also rare but serious side effects associated with this medication that require immediate medical attention. These include severe hypoglycemia, characterized by symptoms like shakiness, anxiety, rapid heartbeat, sweating, confusion, fatigue, and excessive hunger. Serious allergic reactions may present with hives, itching, swelling of the face or tongue, and difficulty breathing. Additionally, dangerously low potassium levels can cause muscle twitches, cramps, abnormal heart rhythms, and fatigue. If you experience any of these serious symptoms, seek urgent medical care.