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This medication comes with important safety warnings and contraindications that you should carefully review. Below are critical points to consider, and you should speak with your healthcare provider if you have any concerns.

• Myasthenic Crisis: Excessive use of pyridostigmine (Mestinon) can lead to muscle weakness. Notably, muscle weakness is also a symptom of worsening myasthenia gravis. Distinguishing whether the weakness is due to too much or too little pyridostigmine can be challenging. Both scenarios can be life-threatening, particularly if respiratory muscles become too weak to function. Be vigilant for severe muscle weakness, even if you are following the prescribed dosage, as this could indicate a myasthenic crisis.

• Use in Asthma Patients: Individuals with asthma should use pyridostigmine (Mestinon) cautiously. Muscle weakness, whether from overuse of the medication or from the progression of myasthenia gravis, can impair breathing. Inform your healthcare provider about any existing lung or breathing conditions prior to initiating pyridostigmine. Seek immediate medical attention if you experience breathing difficulties while on this medication.

• Contraindications: Do not use this medication if you have an intestinal or urinary blockage, as it may pose serious health risks. Discuss any such conditions with your healthcare provider before starting pyridostigmine.

These points are crucial for ensuring safe use of the medication. Always consult your healthcare professional for personalized advice and guidance.

When taking this medication, some individuals may experience common side effects such as nausea, vomiting, diarrhea, abdominal cramps, increased saliva, sweating, runny nose, smaller pupil size, and increased urination. These effects are generally mild, but if they persist or worsen, consulting a healthcare provider is advised.

In addition to these, some users might notice increased muscle cramps, weakness, or twitching. These effects warrant attention, especially if they intensify. It's important to be vigilant about these symptoms and discuss them with a healthcare provider if they occur.

Although rare, severe side effects can occur, such as a myasthenic crisis, which includes severe muscle weakness and trouble breathing. This requires immediate medical attention. Additionally, a very serious allergic reaction is uncommon, but symptoms like rash, itching, severe dizziness, or difficulty breathing necessitate urgent care.

While these are not all possible side effects, they cover the most commonly reported experiences. If you notice any other unusual effects, it's best to contact a healthcare professional for guidance.