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Pyridostigmine

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generic Mestinon

Pyridostigmine, also known as Mestinon, is a medication primarily used to enhance muscle strength in individuals with myasthenia gravis, a condition characterized by muscle weakness. As a cholinesterase inhibitor, Pyridostigmine prevents the breakdown of acetylcholine, a crucial chemical that facilitates communication between nerves and muscles. By inhibiting the enzyme that degrades acetylcholine, this drug ensures more acetylcholine remains available, thereby improving muscle activation and reducing weakness. Pyridostigmine is available in tablet and liquid form and is typically taken multiple times a day. While side effects are uncommon, excessive doses can lead to stomach upset, increased saliva production, and muscle issues. Always consult a healthcare professional for advice tailored to your health needs before starting or changing any medication regimen.
Our coupons are free to use. Before paying, show the pharmacist your Pyridostigmine savings card to get your free discount. Use our filters below to edit the prescription box to match your needs. The Pyridostigmine prices will update based on your prescription needs. Above our Pyridostigmine coupons, you can change your location to see pharmacy prices and costs in other areas. We're here to help you buy Pyridostigmine at the lowest price with our prescription discount card.

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30MG, Pyridostigmine (30 Tablets)

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CVS

$236.64

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Walgreens

$63.75

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Walmart

$206.86

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Rite Aid

$207.72

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Albertsons

$228.82

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Pyridostigmine savings card

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CVS

$236.64

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More prescriptions for myasthenia gravis

coupons from$7.95Save 62%

More prescriptions for myasthenia gravis

Mestinon Save 62%coupons from $7.95

Pyridostigmine dosage forms

The average cost for 30 Tablets of Pyridostigmine (generic Mestinon) at 60MG is $7.95 with a free coupon. This is 0.97% off the average retail price of $821.09
DosageQuantityPrice fromPer unit
60MG30 Tablets$7.95$0.27
30MG30 Tablets$206.86$6.9

Pyridostigmine Warnings

This medication comes with important safety warnings and contraindications that you should be aware of. Please read these carefully and discuss any concerns with your healthcare provider.

  • Myasthenic Crisis Warning: Excessive use of pyridostigmine (Mestinon) can lead to muscle weakness, which is also a symptom of worsening myasthenia gravis. Distinguishing between taking too much or too little pyridostigmine can be challenging, yet both scenarios can be life-threatening if respiratory muscles become too weak. Be vigilant for signs of severe muscle weakness, which can occur even with prescribed use of pyridostigmine, and seek medical attention promptly.

  • Use with Caution in Asthma: Muscle weakness, whether due to excessive pyridostigmine or worsening myasthenia gravis, can impair breathing. Therefore, pyridostigmine should be used cautiously in individuals with asthma or other respiratory issues. Inform your healthcare provider about any existing lung or breathing conditions before beginning treatment. Immediate medical care is necessary if breathing difficulties arise while taking this medication.

  • Contraindications: Pyridostigmine should not be used in individuals with intestinal or urinary blockages, as it poses serious health risks. Consult your healthcare provider if you have these conditions before starting this medication.

Always follow your healthcare provider’s instructions and report any adverse effects or concerns you may encounter during treatment.

Pyridostigmine Side Effects

Common side effects:

  • Nausea
  • Vomiting
  • Diarrhea
  • Abdominal cramps
  • Increased saliva
  • Sweating
  • Runny nose
  • Smaller pupil size
  • Increased urination
  • More frequent bowel movements

Less common but important to monitor:

  • Muscle cramps
  • Twitching
  • Weakness
  • Slow heartbeat
  • Dizziness

Serious side effects:

  • Allergic reaction (rash, itching or swelling, particularly of the face, tongue, or throat, severe dizziness, or difficulty breathing)
  • Myasthenic crisis (severe muscle weakness and trouble breathing)
Pyridostigmine FAQs
What is the drug pyridostigmine used for?

Pyridostigmine is used primarily to treat myasthenia gravis, a condition that causes muscle weakness. It works by improving nerve signals in muscles, thereby enhancing muscle strength. Additionally, it may be used in certain cases to counteract the effects of muscle relaxants after surgery.

Yes, pyridostigmine can cause fatigue as a side effect. While it is primarily used to improve muscle strength in conditions like myasthenia gravis, some individuals may experience tiredness or fatigue. If this side effect is significant or persistent, it is advisable to consult a healthcare provider.

Pyridostigmine increases the activity of acetylcholine in the bowel, which enhances muscle contractions in the gastrointestinal tract. This can help improve bowel motility and alleviate symptoms of conditions like chronic constipation or intestinal pseudo-obstruction.

Pyridostigmine may interact with several types of medications. It is important to avoid taking it with:1. Anticholinergic drugs, such as atropine, which can counteract the effects of pyridostigmine.2. Certain antibiotics, like neomycin and kanamycin, which may reduce its effectiveness.3. Beta-blockers, as they can increase the risk of side effects.4. Other cholinergic drugs, which can enhance the effects and increase the risk of side effects.Patients should always consult with their healthcare provider before starting or stopping any medications to ensure there are no harmful interactions.

Pyridostigmine is generally used to improve muscle strength in individuals with myasthenia gravis, a condition that causes muscle weakness. It works by inhibiting the breakdown of acetylcholine, thereby enhancing communication between nerves and muscles.