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When using Mozobil (plerixafor), it is crucial to be aware of certain safety information and warnings to ensure safe and effective treatment. Please carefully consider the following points and consult with your healthcare provider if you have any questions or concerns:

• Severe Allergic Reactions: Mozobil (plerixafor) can, in rare instances, trigger serious allergic reactions, including anaphylaxis. Healthcare providers will monitor patients during administration and for at least 30 minutes afterward to detect any adverse reactions. Seek immediate medical attention if you experience symptoms such as rash, difficulty breathing, dizziness, or swelling of the lips, tongue, or throat.

• Blood Monitoring: Treatment with Mozobil (plerixafor) alongside G-CSF may lead to alterations in blood cell counts, such as increased white blood cells and decreased platelets. Regular blood tests will be conducted to ensure blood cell counts remain within a safe range.

• Spleen Enlargement: Some individuals receiving Mozobil (plerixafor) with G-CSF have developed an enlarged spleen, which can, in severe cases, lead to spleen rupture—a potentially fatal condition. Report any pain felt in the upper left abdomen or shoulder to your healthcare provider immediately.

• Use During Pregnancy: Animal studies indicate that Mozobil (plerixafor) may harm an unborn baby if used during pregnancy. It is advised to use effective birth control while on Mozobil (plerixafor) treatment and for one week after the last dose to prevent pregnancy. This medication is not recommended for use during pregnancy or breastfeeding.

There are no specific contraindications listed for Mozobil (plerixafor) at this time. Always discuss your medical history and any concerns with your healthcare provider before starting treatment.

When taking this medication, some individuals may experience common side effects such as diarrhea, nausea, vomiting, and gas. You might also notice reactions at the injection site, including redness, swelling, or pain. Additionally, some people feel tired, have headaches, or encounter joint pain. Dizziness and trouble sleeping are less common, yet possible. These effects are generally mild, but if they persist or worsen, it is advisable to consult with a healthcare provider for guidance.

There are other side effects that have been reported, including muscle and bone pain, stomach pain, constipation, bloating, dry mouth, mouth numbness, and excessive sweating. While these are less common, it's important to be aware of them and discuss any concerns with a healthcare professional.

Serious side effects, although rare, demand immediate medical attention. These include severe allergic reactions characterized by rash, trouble breathing, or swelling of the lips, tongue, or throat. Another serious condition is a ruptured spleen, which can present as pain in the left upper abdomen or shoulder. If you experience any of these severe symptoms, seek urgent medical care.

It's essential to monitor your body's response to the medication and communicate any unusual or severe symptoms to a healthcare provider to ensure your safety and well-being.