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Cyclophosphamide

Cyclophosphamide Coupons & Discount Card – Guaranteed Prices from $4392.36

Cyclophosphamide is a chemotherapy medication utilized in the treatment of various cancers in both adults and children, as well as a specific kidney condition known as nephrotic syndrome in children. It functions as an alkylating agent, targeting and damaging the DNA of cancer cells to inhibit their growth and ultimately cause cell death. This drug is often combined with other cancer treatments and can be administered orally or via intravenous injection. While Cyclophosphamide is effective in treating conditions like lymphomas, multiple myeloma, leukemias, mycosis fungoides, ovarian and breast cancers, as well as certain childhood cancers like neuroblastoma and retinoblastoma, it is important to manage potential side effects, such as bladder and kidney issues, by ensuring adequate hydration during treatment. Always consult healthcare professionals for guidance tailored to your individual health needs.
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1GM, Cyclophosphamide (30 Solution Reconstituteds)

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Cyclophosphamide savings card

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Cyclophosphamide dosage forms

The average cost for 30 Solution Reconstituteds of Cyclophosphamide at 1GM is $5329.75 with a free coupon. This is 40.01% off the average retail price of $13320
DosageQuantityPrice fromPer unit
1GM30 Solution Reconstituteds$5329.75$177.66
500MG30 Solution Reconstituteds$1729.6$57.65
2GM30 Solution Reconstituteds$6924.4$230.81

Cyclophosphamide Warnings

The following safety information outlines critical warnings concerning the use of cyclophosphamide. It is important to thoroughly review these details and discuss any concerns with your healthcare provider.

  • Blood Cell Count Reduction: Cyclophosphamide may lead to decreased levels of red and white blood cells and platelets, increasing the risk of anemia, infections, and bleeding. Regular blood tests will be conducted by your provider to monitor these levels. If your counts are low, dosage adjustments may be necessary. Contact your provider immediately if you experience fever, chills, fatigue, or unexplained bleeding or bruising.

  • Kidney and Urinary Tract Concerns: This medication can harm the kidneys and urinary tract, potentially causing hemorrhagic cystitis, a condition where the bladder becomes inflamed and bleeds. To mitigate this risk, maintain hydration and urinate frequently. Mesna (Mesnex) may be prescribed to protect the bladder. Seek medical advice if you notice blood in your urine or experience pain, difficulty urinating, or changes in urine appearance.

  • Cardiac Issues: Cyclophosphamide may induce or exacerbate heart problems, including heart failure, fluid accumulation around the heart, heart muscle inflammation, and irregular heartbeats. Those with pre-existing heart conditions will require additional monitoring. Immediate medical attention should be sought if you encounter chest pain, rapid heartbeat, shortness of breath, leg or foot swelling, sudden weight gain, fatigue, or dizziness.

  • Pulmonary Risks: Rarely, cyclophosphamide may cause lung damage or scarring (pulmonary fibrosis), which can develop over years. Report any persistent cough or breathing difficulties to your provider promptly.

  • Secondary Cancer Risk: There is a rare possibility of developing secondary cancers, such as bladder or blood cancers, following cyclophosphamide treatment. Discuss any concerns regarding cancer risk with your healthcare provider.

  • Liver Damage: Cyclophosphamide can potentially cause liver injury, leading to serious conditions such as hepatic veno-occlusive disease. Regular liver function tests will be conducted. Report any symptoms such as right-side abdominal pain, jaundice, dark urine, fatigue, nausea, vomiting, or appetite loss to your provider immediately.

  • Reproductive Concerns: Cyclophosphamide may harm an unborn baby and increase miscarriage risk. Both males and females should use effective birth control during treatment and continue for at least 4 months (males) or up to 1 year (females) afterward. Notify your provider if pregnancy occurs during this period.

  • Sodium Level Reduction: This medication can result in dangerously low sodium levels in the blood. Symptoms include headache, fatigue, nausea, muscle weakness, cramps, confusion, or seizures. Contact your healthcare provider if these symptoms occur.

Contraindications: Cyclophosphamide should not be used in individuals with conditions that obstruct urine flow from the bladder. Consult your healthcare provider if this applies to you.

Cyclophosphamide Side Effects

Common side effects:

  • nausea
  • vomiting
  • diarrhea
  • loss of appetite
  • hair loss
  • fever

Less common but important to monitor:

  • stomach pain
  • dizziness
  • changes in vision
  • skin rash
  • alterations in skin or nail color

Serious side effects:

  • severe infections
  • significant bleeding or bruising
  • blood in the urine
  • painful urination
  • chest pain
  • shortness of breath
  • rapid heartbeat
  • swelling of the legs or feet
  • severe liver problems
  • seizures
  • anemia
  • increased infection risk
  • easy bruising and bleeding
  • decreased fertility
  • increased long-term cancer risk
  • unexplained weight loss
  • night sweats
  • allergic reaction

Cyclophosphamide Interactions

Interactions with high risk of serious adverse effects and should be avoided:

  • Measles Virus Vaccine, Live
  • Mumps Virus Vaccine, Live
  • Rotavirus Vaccine, Live
  • Rubella Virus Vaccine, Live
  • Varicella Virus Vaccine, Live
  • Zoster Vaccine, Live

Interactions with moderate risk that may require dose adjustment, closer monitoring, or timing changes:

  • Abametapir
  • Adenovirus Vaccine
  • Amprenavir
  • Atazanavir
  • Bacillus of Calmette and Guerin Vaccine, Live
  • Boceprevir
  • Carbamazepine
  • Ceritinib
  • Cholera Vaccine, Live
  • Cobicistat
  • Cyclosporine
  • Darunavir
  • Dengue Tetravalent Vaccine, Live
  • Doxorubicin
  • Doxorubicin Hydrochloride Liposome
  • Eslicarbazepine Acetate
  • Etanercept
  • Fosamprenavir
  • Fosphenytoin
  • Idarubicin
  • Indinavir
  • Influenza Virus Vaccine, Live
  • Lemborexant
  • Lopinavir
  • Nelfinavir
  • Nevirapine
  • Nilotinib
  • Pentostatin
  • Phenytoin
  • Poliovirus Vaccine, Live
  • Ritonavir
  • Saquinavir
  • Smallpox Vaccine
  • St John's Wort
  • Tamoxifen
  • Telaprevir
  • Tipranavir
  • Typhoid Vaccine, Live
  • Warfarin
  • Yellow Fever Vaccine

Interactions with low risk that usually do not require a change in therapy:

Cyclophosphamide FAQs
Is cyclophosphamide a strong chemo?

Yes, cyclophosphamide is considered a strong chemotherapy drug. It is used to treat various types of cancer by interfering with the growth and replication of cancer cells.

Cyclophosphamide is used primarily as a chemotherapy medication to treat various types of cancer, including lymphomas, leukemias, and some solid tumors. It is also used in lower doses as an immunosuppressant to treat certain autoimmune conditions, such as lupus and rheumatoid arthritis.

The major side effect of cyclophosphamide is bone marrow suppression, which can lead to decreased production of blood cells and increase the risk of infections, anemia, and bleeding. Other significant side effects include hemorrhagic cystitis, which is inflammation and bleeding of the bladder, and an increased risk of secondary malignancies.

Cyclophosphamide is a chemotherapy drug that can be toxic, particularly at high doses or with prolonged use. It can cause side effects such as bone marrow suppression, increased risk of infections, bladder irritation, and potential long-term effects like secondary cancers. It is important for patients to be closely monitored by their healthcare provider while receiving this medication to manage and mitigate these risks.

The duration for which a patient can stay on cyclophosphamide depends on the specific condition being treated, the patient's response to the medication, and the occurrence of any side effects. Treatment duration is typically determined by the healthcare provider based on these factors. It is important for patients to have regular follow-ups with their healthcare provider to monitor their response to the medication and adjust the treatment plan as necessary.