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This medication, nilutamide, has been associated with certain serious health risks that require attention. Below are important safety warnings and precautions you should be aware of while using this medication. It is crucial to consult with your healthcare provider if you have any concerns or experience any symptoms.

• Serious Lung Problems: There is a rare chance of developing a severe lung condition known as interstitial pneumonitis while taking nilutamide. This can occur at any time but is most common within the first three months of treatment. Symptoms include cough, difficulty breathing, chest pain, and fever. If any of these symptoms develop, seek medical assistance immediately. Your healthcare provider may conduct chest X-rays and breathing tests prior to starting treatment and continue monitoring your lung health throughout the course of the medication.

• Liver Injury: Nilutamide can occasionally lead to severe liver issues, particularly within the first four months of treatment. Your doctor may perform blood tests to monitor liver function before and during treatment. If you experience symptoms such as yellowing of the skin or eyes, pain in the upper right abdomen, or dark urine, stop taking the medication and contact your healthcare provider promptly.

• Contraindications: Nilutamide should not be used by individuals with severe liver or breathing problems, as it can pose serious health risks. Always consult your healthcare provider to evaluate the suitability of this medication for you.

Adhering to these guidelines and promptly addressing any health concerns with your healthcare provider can help manage your treatment safely.

Common side effects:

• Hot flashes
• Vision changes
• Nausea
• Constipation
• Loss of sexual interest
• Dry skin
• Increased sensitivity to touch and pain
• Weakness
• Headaches
• Trouble sleeping

Serious side effects:

• High blood pressure
• Significant dizziness
• Trouble breathing
• Elevated liver enzymes
• Severe liver issues
• Allergic reaction

Nilutamide (Nilandron) can interact with a number of medications and supplements. It is crucial to inform your healthcare provider about all the medications and supplements you are currently taking, including prescription drugs, over-the-counter products, vitamins, and herbal supplements. Some known interactions include:

• Testosterone and Anabolic Steroids: Products such as testosterone patches, gels, injections, and anabolic steroids, including over-the-counter testosterone precursors like Dhea, may interact with Nilutamide.

• Phenytoin and Fosphenytoin: These medications may increase the risk of side effects when used with Nilutamide. Your doctor might adjust the dosage or frequency of these medications if used together.

• Warfarin: Combining Warfarin with Nilutamide could also raise the risk of side effects. Close monitoring and possible dose adjustments may be necessary.

• Theophylline: Using Theophylline with Nilutamide may result in increased side effects. Your healthcare provider may modify how you take these medications to minimize risks.

Always consult your doctor for personalized advice and before starting or stopping any medication.