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The following safety information outlines crucial warnings associated with the use of Nitro-Bid (nitroglycerin). It is essential to review these details thoroughly and discuss any concerns with your healthcare provider.

• Tolerance: Over time, your body may develop a tolerance to Nitro-Bid (nitroglycerin), reducing its effectiveness. This is more likely if you have used longer-acting nitrates, such as isosorbide mononitrate or isosorbide dinitrate. Increasing the dosage will not improve effectiveness if tolerance develops. To prevent this, follow your prescribed dosage and discuss any increase in chest pain with your healthcare provider. Typically, a nitrate-free period of 10-12 hours is recommended to reduce tolerance risk.

• Low Blood Pressure: Nitro-Bid can cause a significant drop in blood pressure, potentially leading to dizziness, fatigue, or lightheadedness. To minimize these effects, sit down for a few minutes after taking the medication and change positions slowly. Seek immediate medical assistance if you experience fainting, irregular heartbeat, nausea, vomiting, weakness, visual changes, sweating, cold and clammy skin, or increased chest pain. Risks include standing while taking the medication, certain heart conditions, dehydration, use of erectile dysfunction drugs, blood pressure medications, and alcohol consumption.

• Worsening Chest Pain: Nitro-Bid may rarely exacerbate chest pain associated with hypertrophic cardiomyopathy, a condition characterized by thickened heart muscles. If you have this condition, consult your healthcare provider before using this medication. If chest pain worsens after taking a dose, seek emergency medical attention.

• Headache: Headaches are a common side effect when starting Nitro-Bid, especially when changing positions from sitting or lying down to standing. These headaches usually subside as the body adjusts to the medication. If headaches persist or become troublesome, speak with your healthcare professional for potential alternatives.

Contraindications: Nitro-Bid should not be used if you have an allergy to other nitrates such as isosorbide mononitrate or isosorbide dinitrate. If you have such allergies, consult your healthcare provider before using this medication.

In case of overdose, it is crucial to seek emergency medical attention immediately. Always follow your healthcare provider’s instructions for safe and effective use of Nitro-Bid.

When taking this medication, some individuals may experience common side effects such as headaches, dizziness, lightheadedness, nausea, and flushing. These effects are typically mild and may improve over time. For headaches, an over-the-counter pain reliever like acetaminophen or aspirin may be suggested to alleviate discomfort. To minimize the risk of dizziness or lightheadedness, try to rise slowly from sitting or lying down positions.

While many people do not encounter serious issues, it's important to be aware of potential severe side effects. Contact your healthcare provider immediately if you experience fainting, or a rapid, irregular heartbeat. Though rare, allergic reactions can occur, marked by symptoms such as rash, itching, swelling (especially of the face, tongue, or throat), severe dizziness, and trouble breathing. If any of these occur, seek emergency medical care promptly.

Additionally, very low blood pressure may present with symptoms like extreme dizziness, lightheadedness, pale skin, and feeling faint. These require urgent medical attention. Always report any unusual or severe side effects to your healthcare provider to ensure your safety and well-being.