Dihydroergotamine Coupons & Discount Card – Guaranteed Prices from $19.55

This medication has been associated with several serious risks and precautions that must be considered before use. It is crucial to carefully review the following safety information and consult your healthcare provider if you have any concerns or questions.

• Blood Flow Issues: This medication can severely restrict blood flow to the brain and extremities, potentially leading to strokes or tissue damage. The risk increases when combined with certain drugs, including azole antifungals, specific antidepressants, macrolide antibiotics, HIV protease inhibitors, and SSRIs. Always inform your healthcare provider and pharmacist of all medications you are taking to avoid dangerous interactions.

• Cardiac Concerns: Dihydroergotamine may cause blood vessels in the heart to constrict, leading to heart attacks or arrhythmias. Individuals with heart disease or risk factors such as high blood pressure, high cholesterol, smoking, obesity, diabetes, or a family history of heart issues should avoid this medication. It may be advisable to take the first dose under medical supervision to address any immediate complications.

• Stroke Risk: This medication should only be used for migraines as prescribed, as it can increase the risk of stroke and brain damage. Seek immediate medical attention if you experience symptoms such as sudden dizziness, confusion, or weakness on one side of the body.

• Hypertension: Dihydroergotamine can elevate blood pressure, even in those without a history of hypertension. It should not be used by individuals with uncontrolled high blood pressure.

• Rebound Headaches: Overuse of this medication can lead to rebound headaches. Avoid using headache medications, including dihydroergotamine, more than ten days per month unless directed by your provider.

• Pregnancy Risks: This medication is not recommended during pregnancy due to potential harm to the unborn baby and the risk of preterm labor. Animal studies have indicated low birth weight and bone issues in babies due to poor maternal blood flow.

• Fibrosis: Rare cases of fibrosis in the stomach, lungs, or heart have been reported. Use dihydroergotamine only as needed and discuss preventive options with your provider if daily use seems necessary.

• Nasal Spray Irritation: Nasal irritation, including stuffiness, runny nose, or discomfort, is common with the use of Migranal or Trudhesa nasal sprays. Most symptoms resolve within four hours, but consult your provider if they persist or are bothersome.

Contraindications: Avoid using this medication if you have:

• Taken macrolide antibiotics or protease inhibitors
• Taken other vasoconstrictive medications, ergot derivatives, or triptans within 24 hours
• Heart conditions, uncontrolled high blood pressure, or migraines with specific characteristics
• Peripheral arterial disease or have recently undergone blood vessel surgery
• Severe liver or kidney issues
• Are pregnant or breastfeeding

If you experience any severe side effects or suspect an overdose, seek emergency medical assistance immediately. Always ensure that your healthcare provider is aware of your complete medical history and current medications to avoid adverse interactions or contraindications.

Common side effects:

• Dizziness
• Drowsiness
• Headache
• Nausea
• Vomiting
• Diarrhea
• Flushing
• Increased sweating
• Nose, throat, or sinus irritation
• Runny nose
• Change in taste

Serious side effects:

• Signs of poor blood flow (pain, numbness, coldness, or pale color in the hands or feet)
• Heart attack symptoms (chest pain or tightness, pain in the jaw, neck, or back, shortness of breath)
• Stroke symptoms (sudden dizziness, trouble walking or speaking, loss of balance, confusion, weakness on one side of the body)
• High blood pressure symptoms (headaches and vision problems)
• Allergic reactions (rash, itching, swelling, severe dizziness, trouble breathing)

Interactions with high risk of serious adverse effects and should be avoided:

• Almotriptan
• Amprenavir
• Atazanavir
• Azithromycin
• Boceprevir
• Clarithromycin
• Cobicistat
• Cocaine
• Darunavir
• Delavirdine
• Dirithromycin
• Dobutamine
• Dopamine
• Eletriptan
• Ephedrine
• Epinephrine
• Erythromycin
• Fosamprenavir
• Frovatriptan
• Idelalisib
• Indinavir
• Itraconazole
• Josamycin
• Ketoconazole
• Letermovir
• Lidocaine
• Lopinavir
• Mepartricin
• Midodrine
• Mifepristone
• Miokamycin
• Naratriptan
• Nefazodone
• Nelfinavir
• Norepinephrine
• Phenylephrine
• Phenylpropanolamine
• Posaconazole
• Propylhexedrine
• Pseudoephedrine
• Ritonavir
• Rizatriptan
• Rokitamycin
• Roxithromycin
• Saquinavir
• Saralasin
• Spiramycin
• Sumatriptan
• Telaprevir
• Telithromycin
• Tipranavir
• Troleandomycin
• Vasopressin
• Voriconazole
• Zolmitriptan

Interactions with moderate risk that may require dose adjustment, closer monitoring, or timing changes:

• Abametapir
• Alefacept
• Berotralstat
• Bromocriptine
• Ceritinib
• Conivaptan
• Crizotinib
• Dexfenfluramine
• Eluxadoline
• Enzalutamide
• Erdafitinib
• Fluconazole
• Fluvoxamine
• Fosnetupitant
• Imatinib
• Lanreotide
• Lefamulin
• Lorlatinib
• Lumacaftor
• Netupitant
• Octreotide
• Pazopanib
• Propatyl Nitrate
• Ranolazine
• Ribociclib
• Selpercatinib
• Sibutramine
• Tucatinib
• Voxelotor

Interactions with low risk that usually do not require a change in therapy:

• Nitroglycerin
• Propranolol