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The use of Panretin (alitretinoin) requires careful attention to the following safety warnings to avoid potential risks. Please read these points thoroughly and discuss any questions or concerns with your healthcare provider.

• Risk to Unborn Babies: Panretin (alitretinoin) may cause harm to an unborn child. Women who are capable of becoming pregnant should take precautions to avoid pregnancy while using this medication. If you become pregnant or are planning to become pregnant while on this treatment, consult your healthcare provider immediately.

• Increased Sensitivity to Sunlight: This medication can make your skin more sensitive to sunlight, increasing the risk of sunburn. Avoid exposure to sunlamps or tanning beds, and apply sunscreen if you need to be outdoors.

• Interaction with DEET: Do not use products containing DEET, a common ingredient in insect repellents, while using Panretin (alitretinoin). Combining these can lead to increased side effects such as skin irritation, redness, rash, and swelling.

There are currently no known contraindications for Panretin (alitretinoin), but it is important to stay informed and consult your healthcare provider for personalized advice.

When using this medication, some individuals may experience common side effects such as numbness, tingling, dryness, cracking of the skin, mild itching, burning, and skin irritation. These effects are usually mild, but if they persist or worsen, it is advisable to consult a healthcare provider for guidance.

Additionally, other side effects like stinging, flaking, redness, and scaling of the skin have been reported. While these are generally not severe, it's important to monitor them and reach out to a healthcare provider if they become bothersome.

There are also more serious side effects, though they are rare, that require immediate medical attention. These include severe redness, swelling of the skin, blistering, crusting, oozing, peeling, and intense burning or stinging. A serious allergic reaction is also possible, with symptoms such as rash, swelling (particularly of the face, tongue, or throat), severe dizziness, and difficulty breathing. If any of these occur, seek urgent medical care. Always be attentive to how your body responds to the medication and seek professional advice if you notice effects not mentioned here.