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The following information outlines essential safety warnings related to the use of Renova (tretinoin). It is crucial to read and understand these warnings and consult your healthcare provider with any questions or concerns.

• Skin Irritation: Renova (tretinoin) may lead to skin redness, burning, peeling, or swelling. It is important not to exceed the recommended application amount, as this can increase skin irritation without improving results. Individuals with eczema should exercise caution as their skin may already be prone to redness and irritation. If severe skin irritation occurs, contact your healthcare provider. They may advise adjusting the frequency or amount of Renova (tretinoin) used or suggest discontinuing its use altogether, depending on the severity of the reaction. Be particularly cautious if using other skin-irritating medications or if exposed to extreme temperatures.

• Sun Sensitivity: Renova (tretinoin) can heighten your skin's sensitivity to both natural and artificial sunlight, increasing the risk of sunburn. This heightened sensitivity may also contribute to premature skin aging and a higher risk of skin cancer. Those who experience high levels of sun exposure, have skin that burns easily, live in hot climates, or work outdoors should take extra precautions.

• Pregnancy Risk: Use of Renova (tretinoin) during pregnancy can be harmful to an unborn baby. It is advised not to use this medication if you are pregnant or planning to become pregnant. Consult your healthcare provider for alternative treatments for fine wrinkles if you are or could become pregnant.

No specific contraindications are available for Renova (tretinoin), but it is imperative to follow these safety precautions closely.

When using this medication, you might notice some common side effects such as warmth or stinging right after application. In the initial weeks, you may experience skin redness, dryness, itching, scaling, or mild burning. These symptoms often improve with continued use, and a daytime moisturizer can help alleviate dry skin. If these effects persist or worsen, it is important to consult your healthcare provider.

In some cases, more noticeable changes like peeling or a change in the color of the treated skin might occur. Such side effects should be monitored, and any concerns should be discussed with your healthcare provider for further guidance.

Rarely, the medication can cause severe side effects, including blistering or crusting of the skin, severe burning or swelling, or significant changes in skin color. If you experience any of these, it's important to seek medical advice promptly. Additionally, a very serious allergic reaction is uncommon, but if symptoms such as rash, severe dizziness, or trouble breathing occur, immediate medical attention is necessary.

This summary does not cover all possible side effects. If you experience any other unusual symptoms, it's advisable to contact your healthcare provider for more information.