Fluorouracil

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fluorouracil

Fluorouracil, also known as Efudex, is a topical medication used to address certain skin conditions. It belongs to a group of drugs called antimetabolites. This medication is effective for treating actinic keratosis, a precancerous condition often caused by prolonged exposure to ultraviolet light, and basal cell carcinoma, a common form of skin cancer. Fluorouracil impedes the ability of abnormal skin cells to replicate their genetic material, thereby halting their growth. Available as a 5% cream and solution, and a 2% solution, the medication is applied directly to the affected skin areas twice a day for a duration ranging from 2 to 6 weeks, depending on the specific condition being treated. Users might experience side effects such as skin burning, crusting, and irritation. Always consult with a healthcare professional before starting any new treatment to ensure it is appropriate for your condition.
Our Efudex coupons are free to use. You can print the coupon, email it to yourself, or receive the Efudex coupon via text message. To get your free discount, show the pharmacist your Efudex savings card which has the discounted coupon price. Use our filters below to edit the prescription box to match your needs. The Efudex prices will update based on your prescription needs. Above our Efudex coupons, you can change the location to see pharmacy prices in other areas. Our prescription discount card will update online with the specific pharmacy costs associated with your edits. Be sure to text, email, or print the Efudex savings card code that you need after editing the prescription box and location field. Show the discount card to your pharmacist before paying.

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40GM of 5%, Fluorouracil (1 Tube)

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CVS

$37.44

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$32.77

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Albertsons

$39.77

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$74.13

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$101.49

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Efudex savings card

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CVS

$37.44

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Efudex dosage forms

The average cost for 1 Tube of Efudex (fluorouracil) at 40GM of 5% is $32.89 with a free coupon. This is 17.62% off the average retail price of $186.65
DosageQuantityPrice fromPer unit
40GM of 5%1 Tube$32.89$32.89

Efudex Warnings

Fluorouracil (Efudex) topical is a medication with specific safety considerations that are crucial for users to understand. Please ensure you thoroughly review the following information and consult your healthcare provider if you have any questions or concerns:

  • Avoid Sensitive Areas: Do not apply the medication on sensitive skin areas or near mucous membranes, such as around the eyes, mouth, or nose, as this increases the risk of skin damage.

  • Do Not Cover Treated Areas: Refrain from using bandages or dressings over areas where the medication has been applied. Covering these areas can increase absorption, leading to more severe skin-related side effects.

  • Sun Exposure Warnings: The use of fluorouracil can lead to serious skin reactions when exposed to ultraviolet (UV) light, causing painful peeling or blistering. Avoid sun lamps, tanning beds, and try to minimize direct sunlight exposure. If you must be outdoors, consult your dermatologist about using sunscreen and wearing protective clothing, such as hats and long-sleeved shirts.

  • Pregnancy Warning: This medication can cause serious harm to an unborn child, including birth defects and miscarriage. If you are pregnant or planning to become pregnant, inform your dermatologist immediately. This warning is particularly important for females of childbearing age.

  • Rare Toxicity Reaction: In rare cases, individuals with dihydropyrimidine dehydrogenase (DPD) deficiency may experience severe reactions, including stomach pain, bloody diarrhea, vomiting, fever, and inflammation in the mouth, stomach, and intestines. If you have this deficiency, discuss the risks with your healthcare provider.

  • Contraindications: Do not use this medication if you are currently pregnant or have a known DPD deficiency, as it may pose serious health risks. Always consult your healthcare provider if these conditions apply to you.

In case of any adverse reactions or overdose, seek immediate medical attention. These guidelines are designed to ensure your safety while using fluorouracil (Efudex) topical.

Efudex Side Effects

When using this medication, you may experience some common side effects at the application site, including skin irritation, a burning or stinging sensation, redness, dryness, or itchiness. These effects are generally mild and temporary. If they persist or become bothersome, consult your healthcare provider for guidance. Additionally, some individuals may notice temporary hair loss, an abnormal taste in the mouth, or trouble sleeping.

There are also less common side effects that warrant attention, such as darkening of the skin, soreness, or blistering. If you experience skin tenderness, open sores, or a rash, it's important to reach out to your healthcare provider, especially if these symptoms are severe.

More serious side effects, though rare, include stomach pain, bloody diarrhea, vomiting, or signs of infection like persistent sore throat, fever, or chills. If you encounter these or symptoms of a severe allergic reaction—such as rash, severe dizziness, swelling (especially of the face, tongue, or throat), or difficulty breathing—seek immediate medical attention. While these serious reactions are uncommon, they require prompt intervention. Always keep your healthcare provider informed of any side effects you experience with this medication.

Efudex FAQs
What does Efudex do to your face?

Efudex, also known as fluorouracil, is a topical medication used to treat certain skin conditions, such as actinic keratosis and superficial basal cell carcinoma. When applied to the face, Efudex works by targeting and destroying abnormal skin cells. During treatment, patients may experience redness, irritation, peeling, and crusting of the skin as the medication takes effect. These reactions are part of the process as the damaged cells are eliminated. It is important for patients to follow their healthcare provider's instructions and to protect the treated area from sun exposure.

Yes, Efudex (fluorouracil) is a topical form of chemotherapy. It is used to treat certain skin conditions, such as actinic keratosis and superficial basal cell carcinoma, by interfering with the growth of abnormal skin cells.

Yes, Efudix cream should be gently applied to the affected area, but it should not be vigorously rubbed in. It is important to apply a thin layer and allow it to absorb naturally. Always follow the specific instructions provided by a healthcare professional or the medication guide.

Efudex (fluorouracil) is a topical chemotherapy treatment that can be used for superficial basal cell carcinoma. It works by targeting and destroying cancerous cells. However, it is typically used for superficial types and not for more invasive forms of basal cell carcinoma. A healthcare provider should evaluate the specific case to determine if Efudex is an appropriate treatment option.

If there is no reaction to Efudix (fluorouracil), it may indicate that the medication is not effectively treating the condition. It is important for the individual to consult with their healthcare provider to assess the situation. The provider may need to evaluate the treatment plan, confirm the diagnosis, or consider alternative therapies.