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This medication comes with several important safety warnings that you should consider before use. It is crucial to discuss these with your healthcare provider to ensure safe treatment.

• Risk to Unborn Child: The use of Fluorouracil 0.5% cream (Carac) during pregnancy can lead to serious harm to an unborn child, including birth defects and miscarriage. It is essential to inform your dermatologist if you are pregnant or planning to become pregnant while using this medication. This warning is particularly pertinent for females of childbearing potential.

• Rare Toxicity Reaction: Although rare, individuals with a deficiency in dihydropyrimidine dehydrogenase (DPD) may experience a toxicity reaction to Fluorouracil 0.5% cream (Carac). If you have this deficiency, consult your healthcare provider for advice before beginning treatment.

Please note, there are currently no known contraindications for this medication. Always follow your healthcare provider’s instructions and report any unusual symptoms immediately.

When using Carac (fluorouracil topical), it's important to be aware of potential interactions with other substances:

Medications: Carac may interact with certain drugs, including aminolevulinic acid, methoxsalen, porfimer, and verteporfin. These interactions can range from moderate to major in severity. For example, combining Carac with aminolevulinic acid can lead to increased photosensitivity, resulting in severe skin reactions. Therefore, it's crucial to inform your healthcare provider about all medications you're currently taking to avoid adverse effects.

Cannabis Products: Using cannabis while undergoing treatment with Carac can alter the effects of both substances. This combination may increase the risk of side effects such as dizziness, confusion, and respiratory issues. It's advisable to discuss any cannabis use with your healthcare provider to ensure safe and effective treatment.

Sun Exposure: Carac can make your skin more sensitive to sunlight, increasing the risk of sunburn. To protect your skin, limit sun exposure, wear protective clothing, and apply a broad-spectrum sunscreen with a high SPF when outdoors.

Other Skin Products: Avoid using other topical medications, cosmetics, or skin care products on the treated area unless directed by your doctor. Combining Carac with other skin products can lead to increased irritation or reduce the effectiveness of the treatment.

Always consult your healthcare provider before starting or stopping any medication or supplement while using Carac to ensure safe and effective treatment.