Propylene Glycol Coupons & Savings Card – Discount Prices from $0.17
Generic for: Systane balance, Lubricant eye drops, Cvs lubricant drops
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1ML, Propylene Glycol (1 Bottle)
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CVS
$18.16
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Albertsons
$0.17
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Walgreens
$0.17
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Walmart
$1.01
COUPON PRICEPropylene Glycol savings card
Show this card to your pharmacistAlbertsons
$0.17
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011867
LH8CC21459
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LABH001
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Propylene Glycol dosage forms
Dosage Quantity Price from Per unit 1ML 1 Bottle $1.01 $1.01 1ML 2 Bottles $1.01 $0.51 1ML 3 Bottles $1.01 $0.34
| Dosage | Quantity | Price from | Per unit |
|---|---|---|---|
| 1ML | 1 Bottle | $1.01 | $1.01 |
| 1ML | 2 Bottles | $1.01 | $0.51 |
| 1ML | 3 Bottles | $1.01 | $0.34 |
Propylene Glycol Warnings
Propylene glycol is widely used in various products, including foods, cosmetics, and pharmaceuticals, and is generally recognized as safe for these applications. However, certain risks are associated with its use, particularly under specific conditions or in vulnerable populations.
High-Dose or Prolonged Exposure Risks
While typical exposure to propylene glycol is considered safe, consuming large amounts or undergoing prolonged exposure can lead to toxicity. This is especially relevant when propylene glycol is used as a solvent in intravenous medications administered in high doses over a short period. Such scenarios have been linked to adverse effects, including central nervous system issues, hyperosmolarity, hemolysis, cardiac arrhythmias, seizures, agitation, and lactic acidosis.
Vulnerable Populations
Certain groups are more susceptible to the risks associated with propylene glycol:
Infants and Young Children: Due to immature liver and kidney functions, infants and young children may have difficulty metabolizing and excreting propylene glycol, increasing the risk of accumulation and toxicity.
Individuals with Kidney or Liver Disease: Those with impaired kidney or liver function may not efficiently process propylene glycol, leading to higher levels in the body and potential adverse effects.
Patients with Epilepsy: High doses of propylene glycol have been associated with seizures, posing a particular risk to individuals with seizure disorders.
Burn Patients: Extensive use of topical treatments containing propylene glycol on burn patients can result in significant absorption, potentially leading to toxicity.
Environmental Considerations
Propylene glycol is biodegradable and breaks down relatively quickly in the environment. However, when released into water bodies in large quantities, it can deplete oxygen levels, adversely affecting aquatic life. Therefore, proper disposal and management are essential to minimize environmental impact.
Safety Measures
To mitigate the risks associated with propylene glycol:
Monitor Usage: Healthcare providers should be aware of the propylene glycol content in medications, especially when administering high doses or treating vulnerable populations.
Proper Handling: In industrial settings, workers should use protective gear and ensure adequate ventilation to minimize exposure.
Environmental Responsibility: Dispose of propylene glycol-containing products appropriately to prevent environmental contamination.
By understanding and managing these risks, the safe use of propylene glycol can be ensured across its various applications.
Propylene Glycol Side Effects
Propylene glycol is a synthetic liquid commonly used in food, cosmetics, and pharmaceuticals due to its ability to retain moisture and dissolve substances. While generally recognized as safe, some individuals may experience side effects, particularly with high or prolonged exposure. Skin Irritation and Allergic Reactions: Topical application of products containing propylene glycol can occasionally lead to skin irritation, manifesting as redness, itching, or a rash. In rare cases, individuals may develop allergic contact dermatitis, characterized by more severe skin reactions. Respiratory Effects: Inhalation of propylene glycol vapors, such as those from e-cigarettes or theatrical fogs, may cause mild respiratory irritation, including throat discomfort and coughing. Long-term inhalation effects are not well understood, but some studies suggest potential risks, especially in children. Systemic Toxicity: High doses of propylene glycol, particularly when administered intravenously in medical settings, can lead to more serious effects like metabolic acidosis, central nervous system depression, and kidney issues. Such cases are uncommon and typically associated with large, rapid infusions. Vulnerable Populations: Certain groups, including infants, pregnant women, and individuals with liver or kidney disease, may be more susceptible to adverse effects from propylene glycol due to slower metabolism and elimination processes. For most people, exposure to propylene glycol through everyday products is unlikely to cause significant harm. However, those with known sensitivities or underlying health conditions should consult healthcare providers to minimize potential risks.
Propylene Glycol Interactions
Propylene glycol is a common ingredient in various medications, serving as a solvent to dissolve active substances. While generally safe, it can interact with certain drugs and conditions, leading to potential health concerns.
When administered intravenously, especially in large doses or over extended periods, propylene glycol can accumulate in the body. This accumulation may result in metabolic acidosis, a condition where the blood becomes too acidic. Symptoms can include confusion, rapid breathing, and fatigue. Medications such as Lorazepam, Diazepam, Phenytoin, and Nitroglycerin often contain propylene glycol and, when used extensively, can increase the risk of this condition.
Certain individuals are more susceptible to propylene glycol toxicity. Patients with kidney or liver impairments may have difficulty metabolizing and excreting propylene glycol, leading to its buildup. Additionally, infants and young children have immature enzyme systems, making them more vulnerable to its effects.
An important interaction to note is between propylene glycol and Metronidazole, an antibiotic. Metronidazole can inhibit the breakdown of propylene glycol, potentially causing adverse reactions such as nausea, vomiting, headaches, and flushing. Therefore, it's advisable to avoid consuming products containing propylene glycol while taking metronidazole and for at least three days after completing the antibiotic course.
Healthcare providers should monitor patients receiving medications with high propylene glycol content, especially those at risk, to prevent potential toxicity. Being aware of these interactions ensures safer medication use and better patient outcomes.