Provocholine
Brand for: Methacholine
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$140.94
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About Provocholine
Drug Details
Provocholine is a diagnostic medication used to assess bronchial airway hyperreactivity, a characteristic feature of asthma. Administered via inhalation during a methacholine challenge test, it induces controlled narrowing of the airways, allowing healthcare providers to evaluate airway responsiveness. This test is typically conducted in adults and children aged five years and older who do not exhibit overt asthma symptoms. Provocholine should be used with caution, as it can cause significant bronchoconstriction, especially in individuals with certain health conditions. Therefore, it is administered under strict medical supervision, with emergency equipment readily available to manage potential adverse reactions.
Provocholine (Methacholine) dosage forms
| Dosage | Quantity | Price from | Per unit |
|---|---|---|---|
| 18ML | 1 Vial | $146.14 | $146.14 |
| 18ML | 2 Vials | $286.27 | $143.14 |
| 18ML | 3 Vials | $421.82 | $140.61 |
Provocholine FAQs
Provocholine is used in a clinical setting to perform a methacholine challenge test. This test helps diagnose asthma by assessing airway hyperreactivity.
Methacholine chloride is used primarily in a clinical setting to diagnose bronchial hyperreactivity, which is a characteristic of asthma. It is administered during a methacholine challenge test to assess how the airways respond, helping to confirm or rule out asthma in patients with respiratory symptoms.
Methacholine acts as a cholinergic agonist, which means it stimulates the parasympathetic nervous system. In the heart, methacholine can cause a decrease in heart rate (bradycardia) and a reduction in the force of contraction. This is due to its action on muscarinic receptors, which are part of the parasympathetic nervous system's influence on cardiac function.
Methacholine is classified as a cholinergic agonist. It specifically acts as a muscarinic receptor agonist.
Methacholine can affect the heart by causing a decrease in heart rate and a drop in blood pressure. It is a cholinergic agonist that can stimulate the parasympathetic nervous system, leading to these cardiovascular effects. It is important to monitor heart function when methacholine is administered, especially in a clinical setting such as a methacholine challenge test for asthma diagnosis.