Stivarga

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Regorafenib is a medication prescribed for the treatment of colon and rectal cancer, liver cancer, and certain types of digestive system cancer known as gastrointestinal stromal tumors. It functions by inhibiting or halting the proliferation of cancer cells.
Our Stivarga coupons are free to use. You can print the coupon, email it to yourself, or receive the Stivarga coupon via text message. To get your free discount, show the pharmacist your Stivarga savings card which has the discounted coupon price. Use our filters below to edit the prescription box to match your needs. The Stivarga prices will update based on your prescription needs. Above our Stivarga coupons, you can change the location to see pharmacy prices in other areas. Our prescription discount card will update online with the specific pharmacy costs associated with your edits. Be sure to text, email, or print the Stivarga savings card code that you need after editing the prescription box and location field. Show the discount card to your pharmacist before paying.

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40MG, Stivarga (30 Tablets)

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Rite Aid

$8472.45

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$8831.09

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Stivarga dosage forms

The average cost for 30 Tablets of Stivarga at 40MG is $8585.37 with a free coupon. This is 27.95% off the average retail price of $30720.84
DosageQuantityPrice fromPer unit
40MG30 Tablets$8585.37$286.18

Stivarga Warnings

Regorafenib has been linked to rare but potentially fatal liver disease, particularly within the first two months of use. Individuals of Asian descent may face a higher risk. It is important that your healthcare provider conducts regular liver function tests before and throughout your treatment. Immediately inform your doctor if you experience new or worsening symptoms indicative of liver issues, including persistent nausea or vomiting, intense stomach or abdominal pain, dark-colored urine, or yellowing of the eyes and skin.

Stivarga Side Effects

Regorafenib may result in several side effects, ranging from mild to severe. Common mild side effects include diarrhea, mouth or throat sores, taste changes, dry mouth, reduced appetite, hair loss, voice alterations, weight loss, and muscle stiffness. Although these effects are generally manageable, it is important to consult your healthcare provider if they persist or worsen.

On a more serious note, Regorafenib can cause a skin reaction known as hand-foot skin reaction, particularly in individuals of Asian descent. Symptoms such as swelling, pain, redness, peeling, blisters, or tingling in the hands or feet should be reported to your doctor immediately. To prevent exacerbation, avoid excessive heat or pressure on these areas, and protect your skin from sun exposure by wearing sunscreen and protective clothing.

Another potential concern is elevated blood pressure, for which regular monitoring is essential. Serious side effects that require prompt medical attention include slow wound healing, signs of dehydration, mineral imbalance, infection, or underactive thyroid. Additionally, Regorafenib can lead to serious bleeding, characterized by easy bruising, severe abdominal pain, or unusual bleeding from various body parts.

Life-threatening conditions such as heart attack symptoms, sudden back pain, seizures, severe headaches, confusion, vision changes, or one-sided body weakness also necessitate immediate medical intervention. Although rare, severe allergic reactions are possible, and you should seek emergency care if you experience symptoms like rash, swelling, dizziness, or difficulty breathing. Always inform your healthcare provider about any side effects you notice, as this list is not exhaustive.

Stivarga Interactions

Certain medications can interact with this drug, potentially altering its effects or increasing side effects. These include irinotecan and medications that may cause bleeding or bruising, such as clopidogrel, NSAIDs like ibuprofen, and blood thinners such as warfarin. Using aspirin alongside this medication can heighten bleeding risk. Nevertheless, if your doctor has prescribed low-dose aspirin (typically 81-162 milligrams daily) for heart attack or stroke prevention, continue taking it unless advised otherwise by your doctor. Consult your healthcare provider for more details. Additionally, some drugs can influence how your body processes regorafenib, impacting its effectiveness. This includes nefazodone, ritonavir, St. John's wort, telithromycin, azole antifungals (e.g., ketoconazole, itraconazole), macrolide antibiotics (e.g., clarithromycin), HIV protease inhibitors (e.g., nelfinavir), rifamycins (e.g., rifabutin, rifampin), and certain seizure medications like phenytoin.
Stivarga FAQs
Is Stivarga chemotherapy?

Stivarga (regorafenib) is not classified as traditional chemotherapy. It is a type of targeted therapy known as a multikinase inhibitor, which works by blocking specific enzymes that promote cancer cell growth.

Stivarga (regorafenib) is a medication used to treat certain types of cancer, including metastatic colorectal cancer, gastrointestinal stromal tumors, and hepatocellular carcinoma. Its success can vary depending on the individual patient and the specific condition being treated. Clinical trials have shown that Stivarga can help extend progression-free survival and overall survival in some patients. However, the effectiveness and success rate can differ based on factors such as the stage of the cancer, previous treatments, and the patient's overall health. It is important for patients to discuss with their healthcare provider to understand how Stivarga may work for their specific situation.

Stivarga (regorafenib) is a medication that can help slow the growth of tumors and may shrink them in some cases. It is used to treat certain types of cancer, including colorectal cancer, gastrointestinal stromal tumors (GIST), and hepatocellular carcinoma. The effectiveness in shrinking tumors can vary depending on the individual and the specific type of cancer being treated.

The effectiveness of chemotherapy drugs for colon cancer can vary depending on the individual case and stage of the cancer. However, some of the commonly used and potent chemotherapy drugs for colon cancer include 5-fluorouracil (5-FU), oxaliplatin, and irinotecan. These drugs are often used in combination regimens such as FOLFOX (5-FU, leucovorin, and oxaliplatin) or FOLFIRI (5-FU, leucovorin, and irinotecan) to enhance their effectiveness. The choice of treatment should be personalized based on the patient's specific condition and in consultation with an oncologist.

While taking STIVARGA, it is recommended to avoid grapefruit and grapefruit juice. These can interfere with the metabolism of the medication and potentially increase the risk of side effects. It is also advisable to follow any specific dietary guidelines provided by the healthcare provider.