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When taking the medication Stribild, it is crucial to be aware of several important safety warnings. These warnings highlight potential risks and necessary precautions to ensure safe use. Always consult with your healthcare provider if you have any concerns or questions.

• Worsening of Hepatitis B: If you have hepatitis B and stop taking Stribild, your symptoms may worsen significantly. Do not discontinue the medication without your healthcare provider's guidance. If you are advised to stop, ensure regular monitoring of liver function through lab tests. Alert your doctor immediately if you notice any worsening of liver-related symptoms.

• Kidney Function Changes: Stribild may affect kidney function, particularly in those with a history of kidney issues. Regular laboratory tests are recommended to monitor kidney health. Be particularly cautious if you are also taking Viread (tenofovir).

• Liver Problems: Although rare, Stribild can contribute to severe liver issues like lactic acidosis with hepatic steatosis, particularly in women. Symptoms may include loss of appetite, abdominal pain, muscle pain, rapid breathing, extreme fatigue, and sudden weakness. Seek emergency medical attention if these symptoms occur.

• Drug Interactions: Stribild can interact with various medications, potentially increasing their levels and causing harmful side effects, or decreasing the effectiveness of Stribild. Always discuss any new medications or supplements with your healthcare provider or pharmacist before starting or stopping them.

• Bone Problems: The use of Stribild can lead to decreased bone mineral density, increasing the risk of osteoporosis and fractures. Consider taking calcium and vitamin D supplements and discuss with your provider the need for bone density assessments, especially if you have a history of bone fractures or osteoporosis.

• Immune Reconstitution Syndrome: As Stribild reduces the HIV virus in your body, your immune system may strengthen and begin to fight existing infections, potentially causing inflammation. Your healthcare provider may check for underlying infections prior to starting Stribild. Contact your provider if you experience fever, breathing difficulties, or sudden health changes after starting the medication. This is particularly important if your immune system was previously weakened or if you have untreated infections.

These precautions are vital for maintaining health and preventing complications while on Stribild. Always follow your healthcare provider's instructions and report any unusual symptoms or concerns promptly.

When taking this medication, you might experience some common side effects, such as nausea, diarrhea, headaches, dizziness, trouble sleeping, and unusual dreams. These effects are generally mild and often temporary, but if they persist or worsen, it's important to contact your healthcare provider for guidance. Additionally, some individuals may notice changes in the color of their skin on the palms or soles of their feet, or back pain.

In some cases, as your immune system strengthens, it might begin to fight off infections that were already present, potentially bringing back symptoms or causing new ones if the immune system becomes overactive. It's crucial to report any serious symptoms immediately, including unexplained weight loss, persistent severe tiredness, muscle aches, joint pain, numbness or tingling, vision changes, or signs of infection such as a non-healing sore throat, fever, or swollen lymph nodes.

This medication can also lead to serious side effects, although they are rare. Keep an eye out for mental or mood changes, signs of kidney problems, or symptoms indicating liver issues or lactic acidosis. If you experience nausea or vomiting that doesn't stop, loss of appetite, stomach pain, yellowing of the skin or eyes, or dark urine, seek medical attention promptly.

Since tenofovir may increase the risk of bone loss, it is advisable to discuss this with your healthcare provider, especially if you are prone to bone-related issues. They may suggest monitoring your bone mineral density and considering calcium or vitamin D supplements. Severe allergic reactions are uncommon but require immediate medical help if you notice symptoms such as rash, swelling, or difficulty breathing. Always report any other unusual side effects to your healthcare provider.

When taking this medication, be aware of potential interactions with other drugs. It is important not to use this medication alongside adefovir, orlistat, or any other drugs that might affect kidney function, such as acyclovir, cidofovir, ganciclovir, valacyclovir, valganciclovir, and aminoglycosides like amikacin or gentamicin. Additionally, avoid using it with other HIV medications such as ritonavir, or any products containing cobicistat, elvitegravir, emtricitabine, lamivudine, or tenofovir.

This medication can slow the elimination of certain drugs from your system, potentially altering their effectiveness. Affected medications include dronedarone, eletriptan, eplerenone, ergot alkaloids (like ergotamine and dihydroergotamine), salmeterol, tolvaptan, rivaroxaban, some alpha blockers (such as alfuzosin and tamsulosin), certain benzodiazepines (like midazolam and triazolam), certain statins (such as lovastatin and simvastatin), and drugs used to treat erectile dysfunction or pulmonary hypertension (such as avanafil and sildenafil).

Conversely, some drugs can influence how this medication is removed from your body, potentially affecting its efficacy. These include mitotane, rifampin, St. John's wort, and certain seizure medications like carbamazepine, oxcarbazepine, phenobarbital, phenytoin, and primidone.

Moreover, this medication may reduce the effectiveness of hormonal birth control methods, such as pills, patches, or rings, which could lead to pregnancy. It might also heighten some side effects associated with hormonal birth control. Discuss alternative birth control methods with your doctor, and consider using a reliable barrier method, such as latex or polyurethane condoms or dental dams, during sexual activities to help prevent the transmission of HIV. If you experience unusual spotting or breakthrough bleeding, inform your doctor, as these could indicate reduced birth control effectiveness.