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This medication carries important safety information that should be thoroughly understood before starting treatment. Discuss any concerns with your healthcare provider and ensure that you are aware of the following potential risks and necessary precautions:

• Severe Allergic Reactions: Abacavir, a component of this medication, may cause serious, sometimes fatal allergic reactions. Your doctor will conduct a genetic test before initiating treatment to assess your risk. If you test positive or have previously experienced an allergic reaction to abacavir, you should not take this medication. Be vigilant for symptoms such as rash, swelling of the face, tongue, or throat, severe dizziness, trouble breathing, fever, extreme tiredness, nausea, vomiting, diarrhea, stomach pain, muscle aches, sore throat, mouth sores, or cough. If you experience symptoms from two or more of these categories, discontinue use and seek immediate medical attention. Never take abacavir again if you have stopped it due to an allergic reaction. Inform all your healthcare providers of this history and dispose of unused medication properly.

• Hepatitis B Worsening: If you have both hepatitis B and HIV, stopping lamivudine, another component of this medication, can lead to severe hepatitis symptoms. Do not discontinue use without consulting your healthcare provider, who will monitor your liver function for several months post-treatment. Seek medical help if you notice any signs of liver issues.

• Liver Problems: Though rare, this medication can cause life-threatening liver issues, including lactic acidosis with hepatic steatosis, particularly in women. Symptoms include appetite loss, stomach pain, muscle pain, rapid breathing, extreme fatigue, and sudden weakness. If these occur, stop taking the medication and visit an emergency room immediately.

• Immune Reconstitution Syndrome: This condition may occur when your immune system begins to recover, potentially leading to inflammation as it fights off existing infections. Your healthcare provider may check for underlying infections before starting treatment, especially if it is your first time on HIV medication. Contact your provider if you experience fever, difficulty breathing, or sudden health changes after initiating treatment.

• Heart Attack Risk: There may be an increased risk of heart attack for individuals on this medication, particularly those with high blood pressure, high cholesterol, or diabetes. Discuss your medical history and current medications with your healthcare provider to assess your risk.

Always communicate openly with your healthcare provider about your medical history and any concerns to ensure your safety while using this medication.

When taking this medication, you might experience some mild side effects such as headaches, nausea, diarrhea, dizziness, tiredness, or trouble sleeping. These are common and usually not a cause for concern, but if they persist or worsen, it is advisable to consult your healthcare provider.

On rare occasions, your immune system may react to the treatment, which can lead to symptoms of previous infections reappearing, or new symptoms arising if the immune system becomes overactive. This can occur at any point from the start of treatment or even months later. Be vigilant for severe symptoms like unexplained weight loss, persistent muscle aches, severe headaches, joint pain, numbness, vision changes, or signs of infection, and seek medical attention immediately if these occur.

Additionally, you should be aware of the potential for very serious side effects, including pancreatitis, which may present as nausea, vomiting, abdominal pain, or fever. Rare but severe reactions such as liver problems and lactic acidosis can occur, particularly in women and individuals with obesity. Symptoms include persistent nausea, loss of appetite, stomach pain, yellowing of the skin or eyes, dark urine, rapid breathing, or drowsiness. Immediate medical help is crucial if these symptoms develop.

While mental changes like depression or anxiety, easy bruising or bleeding, and signs of anemia are less common, they require prompt consultation with your healthcare provider. Remember, this is not an exhaustive list of side effects. If you notice any other unusual symptoms, reaching out to your healthcare provider is advisable for guidance and management.