Tavalisse

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Fostamatinib, marketed under the brand name Tavalisse, is a medication designed to increase platelet counts in adults suffering from chronic immune thrombocytopenia (ITP), a blood disorder characterized by an abnormally low number of platelets, which can lead to severe bleeding issues. This drug is specifically intended for individuals who have not responded adequately to other treatment options. Fostamatinib functions by inhibiting spleen tyrosine kinase, a protein that plays a role in the immune system's destruction of platelets. By blocking this protein, the drug helps to prevent antibody-mediated platelet destruction. It is administered orally, typically twice a day. Patients should be aware of potential side effects, including high blood pressure, infection, and liver complications, and should consult with healthcare professionals to ensure it is a suitable and safe option for their condition.
Our Tavalisse coupons are free to use. You can print the coupon, email it to yourself, or receive the Tavalisse coupon via text message. To get your free discount, show the pharmacist your Tavalisse savings card which has the discounted coupon price. Use our filters below to edit the prescription box to match your needs. The Tavalisse prices will update based on your prescription needs. Above our Tavalisse coupons, you can change the location to see pharmacy prices in other areas. Our prescription discount card will update online with the specific pharmacy costs associated with your edits. Be sure to text, email, or print the Tavalisse savings card code that you need after editing the prescription box and location field. Show the discount card to your pharmacist before paying.

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100MG, Tavalisse (30 Tablets)

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Rite Aid

$7635.31

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$7958.65

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Tavalisse savings card

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Rite Aid

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Tavalisse dosage forms

The average cost for 30 Tablets of Tavalisse at 100MG is $7738.15 with a free coupon. This is 27.95% off the average retail price of $27688.07
DosageQuantityPrice fromPer unit
100MG30 Tablets$7738.15$257.94
150MG30 Tablets$7738.15$257.94

Tavalisse Warnings

When considering the use of Tavalisse (fostamatinib), it is crucial to be aware of several safety warnings to ensure proper management of potential risks. Below are key precautions and actions to consider:

  • High Blood Pressure: Tavalisse may increase blood pressure, particularly if you already have hypertension. Regular monitoring is essential—every two weeks initially, then monthly once stable. Adjustments to your blood pressure medication or the Tavalisse dose may be necessary if hypertension persists. Seek immediate medical help if you experience severe symptoms such as vision changes, chest pain, severe headache, nausea, vomiting, anxiety, or breathing difficulties.

  • Pregnancy Risks: Tavalisse is not recommended during pregnancy due to potential harm to the unborn baby, as evidenced by animal studies. If you are pregnant or planning to become pregnant, consult your healthcare provider. Women who can become pregnant should use effective birth control during treatment and for one month after the last dose.

  • Liver Health: Rarely, Tavalisse can cause liver issues. Monthly blood tests are required to monitor liver function. If liver problems are suspected, your healthcare provider may pause treatment to evaluate the cause. Immediate medical attention is necessary if you notice symptoms like yellowing of the skin or eyes, fatigue, loss of appetite, nausea, stomach pain, confusion, or mood changes.

  • White Blood Cell Counts: The medication may reduce white blood cell counts, heightening the risk of infections. Monthly checks of your WBC count are important. If your count is too low, your provider might need to lower the dose or halt the medication. Contact your provider if you experience infection symptoms such as fever, cough, chills, body aches, or fatigue.

  • Diarrhea: This is a common side effect of Tavalisse. If diarrhea occurs, communicate with your healthcare provider promptly. Treatment may involve dietary adjustments, increased fluid intake, and possibly antidiarrheal medicines like loperamide. Dose reduction or discontinuation of Tavalisse might be necessary if diarrhea persists.

In case of any signs of overdose or severe reactions, seek emergency medical assistance immediately. Always discuss any concerns or symptoms with your healthcare provider to ensure safe and effective use of Tavalisse.

Tavalisse Side Effects

When taking this medication, some common side effects include diarrhea, high blood pressure, nausea, dizziness, and tiredness. These symptoms are generally mild, but if they persist or worsen, it is advisable to consult with your healthcare provider. Additionally, this medication may cause symptoms associated with infections like fever, cough, or congestion, as well as high liver enzymes.

It is important to be aware of other potential side effects such as rash, stomach pain, fatigue, and chest pain. Some individuals may also experience a low white blood cell count. If any of these side effects occur, especially in a severe form, contacting your healthcare provider is recommended.

There are rare but serious side effects that require immediate medical attention. These include dangerously high blood pressure, which can manifest as chest pain, severe headache, nausea, vomiting, anxiety, shortness of breath, or changes in vision. Serious liver problems can present as yellowing of the skin or eyes, confusion, fatigue, low appetite, nausea, or stomach discomfort. Additionally, the medication may increase your susceptibility to serious infections, presenting symptoms such as fever, tiredness, body aches, chills, or difficulty breathing.

In rare cases, severe allergic reactions may occur, characterized by rash, itching, swelling, severe dizziness, or trouble breathing. Immediate medical help should be sought if any of these serious symptoms are experienced. Always keep your healthcare provider informed about any side effects you encounter.

Tavalisse Interactions

Certain medications can influence how fostamatinib is processed in your body, potentially altering its effectiveness. These include azole antifungals like ketoconazole and itraconazole, rifamycins such as rifampin, herbal supplements like St. John's wort, and seizure medications such as carbamazepine and phenytoin.
Tavalisse FAQs
What is Tavalisse used for?

Tavalisse is used for the treatment of thrombocytopenia in adults with chronic immune thrombocytopenia (ITP) who have had an insufficient response to previous treatment.

The cost of Tavalisse can vary depending on factors such as the pharmacy, location, insurance coverage, and any available discounts or patient assistance programs. It is recommended to contact a local pharmacy or healthcare provider for the most accurate and up-to-date pricing information. Additionally, patients may inquire about financial assistance programs that could help reduce the cost.

Yes, Tavalisse (fostamatinib) is considered an immunosuppressant. It works by inhibiting certain enzymes that play a role in the immune response, which can help reduce the destruction of platelets in conditions like chronic immune thrombocytopenia (ITP).

The success rate of Tavalisse (fostamatinib) can vary depending on the specific condition being treated and individual patient factors. In clinical trials for chronic immune thrombocytopenia (ITP), Tavalisse demonstrated a significant improvement in platelet counts for many patients. Approximately 18% of patients achieved a stable platelet response compared to 2% in the placebo group. It is important for patients to discuss with their healthcare provider to understand how Tavalisse may work for their specific situation.

An alternative to Tavalisse (fostamatinib) for the treatment of chronic immune thrombocytopenia (ITP) may include other medications such as corticosteroids, intravenous immunoglobulin (IVIG), or thrombopoietin receptor agonists like eltrombopag (Promacta) and romiplostim (Nplate). The choice of treatment should be based on the patient's specific condition and medical history, and it is important to consult with a healthcare provider to determine the most appropriate option.

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