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When considering the use of Tavalisse (fostamatinib), it is crucial to be aware of several safety warnings to ensure proper management of potential risks. Below are key precautions and actions to consider:

• High Blood Pressure: Tavalisse may increase blood pressure, particularly if you already have hypertension. Regular monitoring is essential—every two weeks initially, then monthly once stable. Adjustments to your blood pressure medication or the Tavalisse dose may be necessary if hypertension persists. Seek immediate medical help if you experience severe symptoms such as vision changes, chest pain, severe headache, nausea, vomiting, anxiety, or breathing difficulties.

• Pregnancy Risks: Tavalisse is not recommended during pregnancy due to potential harm to the unborn baby, as evidenced by animal studies. If you are pregnant or planning to become pregnant, consult your healthcare provider. Women who can become pregnant should use effective birth control during treatment and for one month after the last dose.

• Liver Health: Rarely, Tavalisse can cause liver issues. Monthly blood tests are required to monitor liver function. If liver problems are suspected, your healthcare provider may pause treatment to evaluate the cause. Immediate medical attention is necessary if you notice symptoms like yellowing of the skin or eyes, fatigue, loss of appetite, nausea, stomach pain, confusion, or mood changes.

• White Blood Cell Counts: The medication may reduce white blood cell counts, heightening the risk of infections. Monthly checks of your WBC count are important. If your count is too low, your provider might need to lower the dose or halt the medication. Contact your provider if you experience infection symptoms such as fever, cough, chills, body aches, or fatigue.

• Diarrhea: This is a common side effect of Tavalisse. If diarrhea occurs, communicate with your healthcare provider promptly. Treatment may involve dietary adjustments, increased fluid intake, and possibly antidiarrheal medicines like loperamide. Dose reduction or discontinuation of Tavalisse might be necessary if diarrhea persists.

In case of any signs of overdose or severe reactions, seek emergency medical assistance immediately. Always discuss any concerns or symptoms with your healthcare provider to ensure safe and effective use of Tavalisse.

When taking this medication, some common side effects include diarrhea, high blood pressure, nausea, dizziness, and tiredness. These symptoms are generally mild, but if they persist or worsen, it is advisable to consult with your healthcare provider. Additionally, this medication may cause symptoms associated with infections like fever, cough, or congestion, as well as high liver enzymes.

It is important to be aware of other potential side effects such as rash, stomach pain, fatigue, and chest pain. Some individuals may also experience a low white blood cell count. If any of these side effects occur, especially in a severe form, contacting your healthcare provider is recommended.

There are rare but serious side effects that require immediate medical attention. These include dangerously high blood pressure, which can manifest as chest pain, severe headache, nausea, vomiting, anxiety, shortness of breath, or changes in vision. Serious liver problems can present as yellowing of the skin or eyes, confusion, fatigue, low appetite, nausea, or stomach discomfort. Additionally, the medication may increase your susceptibility to serious infections, presenting symptoms such as fever, tiredness, body aches, chills, or difficulty breathing.

In rare cases, severe allergic reactions may occur, characterized by rash, itching, swelling, severe dizziness, or trouble breathing. Immediate medical help should be sought if any of these serious symptoms are experienced. Always keep your healthcare provider informed about any side effects you encounter.