Tybost

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Cobicistat, also known as Tybost, is a medication used to enhance the effectiveness of certain HIV treatments, specifically atazanavir and darunavir. It works by inhibiting an enzyme in the liver called CYP3A4, which is responsible for metabolizing many medications, including these HIV antiretrovirals. By slowing down this enzyme, cobicistat increases the levels of these medications in the body, helping to better control HIV infection. Although cobicistat is not a cure for HIV, it plays a crucial role in managing the condition when used in combination with other HIV medications. To minimize the risk of spreading HIV, it is important to continue taking all prescribed HIV medications and use effective barrier methods, such as condoms or dental dams, during sexual activity. Additionally, do not share personal items that may have been in contact with blood or other body fluids. Always consult your healthcare provider for personalized advice and follow their guidance for safe and effective treatment.
Our Tybost coupons are free to use. You can print the coupon, email it to yourself, or receive the Tybost coupon via text message. To get your free discount, show the pharmacist your Tybost savings card which has the discounted coupon price. Use our filters below to edit the prescription box to match your needs. The Tybost prices will update based on your prescription needs. Above our Tybost coupons, you can change the location to see pharmacy prices in other areas. Our prescription discount card will update online with the specific pharmacy costs associated with your edits. Be sure to text, email, or print the Tybost savings card code that you need after editing the prescription box and location field. Show the discount card to your pharmacist before paying.

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150MG, Tybost (30 Tablets)

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CVS

$306.89

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$304.47

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$318.68

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$326.74

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Tybost savings card

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Tybost dosage forms

The average cost for 30 Tablets of Tybost at 150MG is $306.89 with a free coupon. This is 27.37% off the average retail price of $1121.25
DosageQuantityPrice fromPer unit
150MG30 Tablets$306.89$10.23

Tybost Warnings

The following safety information outlines important warnings associated with the use of Tybost (cobicistat). Please read carefully and discuss any concerns with your healthcare provider.

  • Kidney Function Changes: Tybost (cobicistat) may lead to alterations in kidney function or cause kidney damage, especially in individuals with a history of kidney issues or those taking older versions of tenofovir as part of their HIV antiretroviral therapy (ARV) regimen. Regular monitoring through blood tests is advised to assess kidney function. Increased risk is associated with a history of kidney damage and the use of Viread (tenofovir).

  • Drug Interactions: Tybost (cobicistat) can interact with a wide range of medications, potentially increasing the levels of these drugs in the body, which may result in serious or life-threatening side effects. Conversely, some medications can reduce the effectiveness of Tybost (cobicistat) and the ARVs it boosts. It is crucial to consult your healthcare provider or pharmacist before beginning or discontinuing any medications or supplements.

  • Use with Other HIV ARVs: Tybost (cobicistat) can enhance your HIV ARV regimen but is only approved for use with certain protease inhibitors, such as atazanavir (Reyataz) and once-daily darunavir (Prezista). It is not suitable for use with twice-daily darunavir or many NNRTIs, including Sustiva (efavirenz). Although similar to Norvir (ritonavir) as a booster, Tybost (cobicistat) cannot replace Norvir (ritonavir) in an HIV treatment plan. It is important not to combine Tybost (cobicistat) with Norvir (ritonavir) in any regimen.

Please follow all instructions provided by your healthcare provider to ensure safe and effective use of Tybost (cobicistat).

Tybost Side Effects

When taking this medication, some individuals may experience common side effects that are generally mild, such as nausea and diarrhea. If these persist or worsen, it is advisable to consult with a healthcare provider. Additionally, headaches and high blood sugar have been reported by some users. A small percentage of individuals may notice a rash or yellowing of the skin and eyes; monitor these symptoms and seek advice if they become concerning.

In some cases, the immune system may become overactive, which can lead to the reemergence of previous infections or the onset of new symptoms. Serious symptoms requiring immediate medical attention include unexplained weight loss, persistent severe tiredness, muscle aches, ongoing headaches, joint pain, and numbness or tingling in the extremities. Vision changes and signs of an infection, such as fever or swollen lymph nodes, also warrant prompt medical evaluation.

Rare but severe side effects include allergic reactions characterized by rash, itching, hives, or swelling of the face, lips, tongue, or throat. Kidney injuries, indicated by a decrease in urine output and swelling of the ankles, hands, or feet, are serious and require urgent care. Unusual thyroid activity, marked by irritability and a fast or irregular heartbeat, should be addressed immediately. Always seek medical help if you notice any severe or unusual symptoms not listed here.

Tybost Interactions

Certain medications can interact with this drug, potentially altering its effectiveness or the way it works in your body. Some drugs that may be affected by this medication include elvitegravir, orlistat, and ritonavir. This medication may slow the elimination of other drugs from your system, influencing their performance. Affected medications can include specific alpha blockers (like alfuzosin and tamsulosin), benzodiazepines (such as midazolam and triazolam), dronedarone, ergot alkaloids (including dihydroergotamine and ergotamine), quinidine, pimozide, ranolazine, rivaroxaban, salmeterol, drugs for erectile dysfunction or pulmonary hypertension (such as avanafil and sildenafil), and certain cholesterol-lowering statins (like lovastatin and simvastatin).

Additionally, some medications may impact how this drug, cobicistat, is processed in your body, thereby affecting its function. Examples include certain seizure medications (such as carbamazepine, phenobarbital, phenytoin, and primidone), enzalutamide, certain HIV NNRTI medications (like efavirenz, etravirine, and nevirapine), mitotane, rifampin, and St. John's wort.

It's important to note that this medication might reduce the effectiveness of hormonal birth control methods, such as pills, patches, or rings, potentially leading to pregnancy. Discuss with your healthcare provider whether you should use an additional, reliable form of birth control while taking this medication. Inform your doctor if you experience any unusual spotting or breakthrough bleeding, as this could indicate that your birth control is not functioning properly.

Lastly, avoid using this medication alongside any other products that contain cobicistat.

Tybost FAQs
What is Tybost used for?

Tybost is used as a pharmacokinetic enhancer to increase the effectiveness of certain antiretroviral medications in the treatment of HIV-1 infection. It is not used as an antiretroviral agent on its own but is combined with other medications to boost their levels in the body.

The cost of Tybost can vary depending on factors such as the pharmacy, location, and whether the patient has insurance coverage. It is recommended to check with local pharmacies or insurance providers for the most accurate and up-to-date pricing information. Additionally, some pharmaceutical companies offer patient assistance programs that may help reduce the cost for eligible individuals.

Cobicistat is classified as a pharmacokinetic enhancer. It is used to boost the effectiveness of certain antiretroviral drugs by inhibiting enzymes that metabolize these drugs, thereby increasing their concentration in the blood.

Cobicistat is not an antiviral. It is a pharmacokinetic enhancer used to increase the effectiveness of certain antiretroviral drugs by inhibiting enzymes that metabolize these drugs, thereby boosting their levels in the body.

Ritonavir and cobicistat are both pharmacokinetic enhancers used to boost the effectiveness of certain antiretroviral drugs by inhibiting the enzyme CYP3A4, which metabolizes these drugs. The primary difference between the two is that ritonavir is also an antiretroviral agent with its own antiviral activity, whereas cobicistat has no antiviral activity and is used solely as a booster. Additionally, ritonavir can induce some liver enzymes, while cobicistat is more selective and does not have this effect.

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