Febuxostat

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febuxostat

Febuxostat is a medication prescribed to lower uric acid levels in individuals with gout, particularly for those who cannot take allopurinol or have not found it effective. It works by inhibiting an enzyme called xanthine oxidase, responsible for producing uric acid in the body. By reducing uric acid levels, febuxostat helps prevent gout attacks and kidney stones. Due to potential risks of serious heart-related issues and stroke, febuxostat is recommended only when other treatments like allopurinol are not suitable, ineffective, or cause significant side effects. Always consult your healthcare provider before starting any new medication.
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40MG, Febuxostat (30 Tablets)

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CVS

$20.70

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$14.82

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$18.00

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$26.29

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$83.70

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Uloric dosage forms

The average cost for 30 Tablets of Uloric (febuxostat) at 40MG is $14.26 with a free coupon. This is 12.13% off the average retail price of $117.59
DosageQuantityPrice fromPer unit
40MG30 Tablets$14.26$0.48
80MG30 Tablets$17.27$0.58

Uloric Warnings

Febuxostat is a medication that requires careful consideration due to its potential risks. It is important to discuss any concerns with your healthcare provider before starting treatment. Here are key safety and warning points to be aware of:

  • Heart-Related Risks: Febuxostat may increase the risk of severe heart-related side effects such as heart attack, stroke, or other potentially fatal cardiac issues. Patients with a history of heart disease, angina, heart attack, or stroke should notify their doctor, as these conditions can heighten the risk. Immediate medical attention is necessary if you experience symptoms like chest or jaw pain, sweating, breathlessness, irregular heartbeat, dizziness, fainting, unilateral weakness, sudden vision changes, confusion, speech difficulties, or a sudden severe headache.

  • Increased Gout Attacks: During the initial weeks of febuxostat treatment, there may be an increase in gout attacks due to fluctuating uric acid levels. Your healthcare provider may prescribe an additional medication to manage this during the early phase of treatment.

  • Liver Damage: Although rare, febuxostat can cause severe liver damage. Regular liver function tests will be conducted by your provider, and the treatment may be discontinued if abnormalities are detected. Signs of liver issues include yellowing of the skin or eyes, which should be reported to your provider immediately.

  • Serious Skin Reactions: There is a potential for severe skin reactions in some individuals. If you have previously experienced a skin reaction to allopurinol (Zyloprim), you may be at risk with febuxostat. Discontinue use and contact your healthcare provider immediately if you notice any signs of red, swollen, blistered, or peeling skin.

  • Contraindications: Febuxostat should not be used if you are taking azathioprine (Imuran) or mercaptopurine, as these combinations can pose serious health risks. Consult your healthcare provider if you are on these medications.

Always follow your doctor's recommendations and inform them of any other medications or supplements you are taking. In the case of an overdose, seek emergency medical attention immediately. Your healthcare provider is your best resource for ensuring safe and effective use of febuxostat.

Uloric Side Effects

When taking this medication, some common side effects might occur, though they are usually mild and temporary. These include changes in liver function tests, mild rashes, nausea, and joint pain. If these effects persist or worsen, consulting a healthcare provider is advisable for reassurance and guidance.

There are other possible side effects that, while less common, may still occur. These include ringing in the ears, blurry vision, vomiting, upset stomach, gas, heartburn, stomach ulcers, changes in taste and appetite, dehydration, low blood cell counts, muscle pain, anxiety, trouble sleeping, mood changes, and alterations in hair growth and color. Additionally, cold and flu-like symptoms might be experienced. If any of these symptoms become severe, it is important to seek medical advice.

Serious side effects, though rare, require immediate medical attention due to their severity. These include serious skin reactions such as red, swollen, blistered, or peeling skin, as well as signs of liver problems like yellowing of the skin or eyes, persistent nausea or vomiting, stomach upset, dark urine, and itchiness. Additionally, chest pain is a serious concern that warrants urgent medical care. If you notice any of these severe symptoms, it is crucial to get medical help right away.

Uloric Interactions

Some products that may interact with this drug include: azathioprine, mercaptopurine.
Uloric FAQs
Who should not take Uloric?

Uloric (febuxostat) should not be taken by individuals with a history of severe hypersensitivity to febuxostat or any of its components. It is also not recommended for patients with ischemic heart disease or congestive heart failure due to an increased risk of cardiovascular events. Additionally, those with severe kidney or liver impairment should use caution and consult their healthcare provider before taking Uloric. It is important for patients to discuss their full medical history with their healthcare provider to determine if Uloric is appropriate for them.

Uloric is used to lower uric acid levels in the blood for patients with gout. It helps prevent gout attacks by reducing the production of uric acid.

A healthcare provider may consider alternatives to colchicine based on the specific condition being treated. For gout, nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or naproxen, or corticosteroids, may be used as substitutes. For familial Mediterranean fever, other options might include NSAIDs or biologics, depending on the patient's response and tolerance. It is important for the patient to consult with their healthcare provider to determine the most appropriate alternative based on their individual medical needs.

Febuxostat carries a black box warning for an increased risk of cardiovascular death. Patients with a history of cardiovascular disease should be monitored closely, and healthcare providers should consider the risks and benefits when prescribing febuxostat.

Uloric (febuxostat) is a medication used to lower uric acid levels in people with gout. While it is intended to help manage gout, it can sometimes cause an increase in gout flares, especially when first starting the medication. This is because as uric acid levels decrease, urate crystals in the joints may become more mobile, potentially triggering a flare. It is common for healthcare providers to prescribe additional medications, such as colchicine or NSAIDs, to help manage these initial flares when starting Uloric.