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While taking this medication, you might experience mild side effects such as nausea, vomiting, dry mouth, dizziness, drowsiness, blurred vision, or constipation. These symptoms are generally temporary, but if they persist or worsen, it's important to inform your healthcare provider. To manage dry mouth, consider using sugarless candy or gum, drinking water, or trying saliva substitutes. A harmless and temporary change in urine or stool color to blue-green may also occur while on this medication.

In some cases, more serious side effects can arise, requiring prompt medical attention. These include hot, dry, flushed skin, decreased sweating, eye pain, difficulty urinating, or signs of kidney problems, such as changes in urine output or painful urination. Seek immediate medical help if you experience symptoms like easy bruising or bleeding, black or tarry stools, severe stomach pain, vomit resembling coffee grounds, or signs of liver issues like persistent nausea, unusual fatigue, dark urine, or yellowing of the skin or eyes.

Rarely, this drug may trigger a hypertensive crisis, a potentially life-threatening condition characterized by severe headache, irregular heartbeat, chest pain, neck stiffness, intense nausea, clammy skin, dilated pupils, vision changes, or sudden light sensitivity. If these symptoms occur, urgent medical intervention is necessary.

Allergic reactions to this medication are uncommon but can be serious. Watch for signs like rash, itching, swelling (particularly of the face, tongue, or throat), severe dizziness, or trouble breathing, and seek medical help immediately if they occur. Always contact your healthcare provider if you notice any other unusual symptoms.

This medication can interact with a variety of other products. Some of these include Apraclonidine, Atomoxetine, bupropion, Carbamazepine, dichlorphenamide, Methotrexate, Mifepristone, potassium supplements, pramlintide, Tetrabenazine, specific Parkinson's disease medications (such as Entacapone, Levodopa, Tolcapone), certain blood pressure medications (like guanethidine, Methyldopa), sulfonamide drugs (including sulfa antibiotics such as Sulfamethoxazole), and sympathomimetics (like amphetamine, ephedrine). Additionally, products that reduce urine acidity, such as antacids, Sodium Bicarbonate, and potassium/sodium citrate, may also interact with this medication.

This medication could raise the risk of bleeding if taken with other drugs that cause bleeding, such as anti-platelet medications like Clopidogrel or blood thinners like Dabigatran, Enoxaparin, or Warfarin.

Combining this medication with other MAO inhibitors can lead to a serious and potentially fatal interaction. Avoid using other MAO inhibitors (such as isocarboxazid, Linezolid, Metaxalone, moclobemide, phenelzine, procarbazine, Rasagiline, safinamide, Selegiline, or Tranylcypromine) during treatment and for two weeks before and after treatment with this medication. Consult your doctor for guidance on when to start or stop using this medication.

Inform your healthcare provider if you are taking any drugs that could increase the risk of dangerously high blood pressure when combined with this medication. This includes herbal products like ephedra, nasal decongestants such as phenylephrine or pseudoephedrine, stimulants like amphetamines or Epinephrine, and diet aids. Avoid using this medication with these products. Speak with your doctor or pharmacist for more information.

If you are also using azole antifungal drugs (for example, Itraconazole or Ketoconazole), take this medication at least two hours after the antifungal.

Review all your prescription and over-the-counter medicine labels, as many contain pain relievers/fever reducers like Aspirin or NSAIDs such as Ibuprofen, Ketorolac, or Naproxen. These are similar to salicylate and could increase the risk of side effects when taken together. However, if your doctor has advised you to take low-dose aspirin (usually 81-162 milligrams per day) to prevent heart attack or stroke, continue taking it unless otherwise directed by your doctor. Consult your doctor or pharmacist for more details.

Inform your healthcare provider if you are using other products that cause drowsiness, including alcohol, marijuana (cannabis), antihistamines like Cetirizine or diphenhydramine, sleep or anxiety medications such as Alprazolam, Diazepam, or Zolpidem, muscle relaxants, and opioid pain relievers like codeine.

Check the labels on all your medications (such as those for allergies or cough-and-cold) since they may contain ingredients that cause drowsiness. Consult your pharmacist on how to use these products safely.

This medication may interfere with certain lab tests, possibly resulting in inaccurate test results. Ensure that all your healthcare providers and lab personnel are aware that you are using this medication.