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When taking this medication, you might experience nausea, vomiting, dry mouth, dizziness, drowsiness, blurred vision, or constipation. These common side effects are usually mild, and there are ways to manage them. For instance, to alleviate dry mouth, consider using sugarless candy or gum, sipping water, or using a saliva substitute.

One harmless side effect you may notice is a blue-green tint in your urine or stool, which will disappear once you stop taking the medication. Most people find the benefits of the medication outweigh these minor side effects.

However, be alert for more serious side effects, such as hot, dry, flushed skin, decreased sweating, eye pain, or difficulty urinating, which might indicate kidney problems. In such cases, contact your healthcare provider promptly.

Seek immediate medical attention if you experience severe symptoms like easy bruising or bleeding, black or tarry stools, intense stomach pain, or vomit resembling coffee grounds. These could be signs of liver issues or gastrointestinal bleeding.

In rare instances, this medication may trigger a hypertensive crisis, a potentially fatal condition. Watch for severe headaches, irregular heartbeat, chest pain, or sensitivity to light. Also, be aware of signs of a severe allergic reaction, such as rash, swelling of the face, or difficulty breathing, and seek urgent medical care if they occur.

If you notice any other unusual effects, it's important to reach out to your healthcare provider to discuss them.

This medication can interact with several other drugs and products. It may affect or be affected by apraclonidine, atomoxetine, bupropion, carbamazepine, dichlorphenamide, methotrexate, mifepristone, potassium supplements, pramlintide, tetrabenazine, specific Parkinson's medications (such as entacapone, levodopa, tolcapone), some blood pressure medicines (like guanethidine, methyldopa), sulfonamide drugs (including certain antibiotics like sulfamethoxazole), and sympathomimetics (such as amphetamine, ephedrine). Products that lower urine acidity, like antacids and sodium bicarbonate, can also interact.

Using this medication with others that increase bleeding risk, like anti-platelet drugs (such as clopidogrel) and anticoagulants (like dabigatran, enoxaparin, warfarin), can heighten bleeding risks. Additionally, combining this with other MAO inhibitors (for example, isocarboxazid, linezolid, and phenelzine) can lead to a dangerous reaction. It's crucial to avoid these combinations and consult your doctor about when to start or stop these medications.

Inform your healthcare provider if you're using products that might cause dangerously high blood pressure when used with this medication. These include herbal supplements (like ephedra), nasal decongestants (such as phenylephrine), stimulants (like amphetamines), and diet aids. Avoid using this medication with these products.

If you're taking azole antifungal medications (like itraconazole or ketoconazole), ensure you take this medication at least two hours after the antifungal. Carefully read labels on all prescriptions and over-the-counter drugs, as many contain pain relievers or fever reducers (like aspirin and NSAIDs) that could increase side effects when paired with this medication. However, if your doctor has advised you to take low-dose aspirin for heart protection, continue taking it unless directed otherwise.

Inform your doctor or pharmacist if you're using other substances that cause drowsiness, such as alcohol, marijuana, antihistamines (like cetirizine), sleep or anxiety drugs (such as alprazolam), muscle relaxants, and opioid painkillers (like codeine). Check all your medication labels for ingredients that may induce drowsiness, and consult your pharmacist about their safe use.

This medication might affect certain lab tests, possibly leading to false results. Ensure all medical personnel and your doctors are aware that you are using this medication.