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The following safety warnings are crucial for understanding the potential risks and necessary precautions associated with the use of Vimpat (lacosamide). It is important to review these thoroughly and discuss any concerns with your healthcare provider.

• Risk of Suicidal Thoughts and Behavior: Antiepileptic medications like Vimpat may increase the risk of suicidal thoughts or behaviors. Monitor for any new or worsening depression, mood changes, or behavioral changes, particularly during the initial months of treatment or when adjusting the dosage. Report any concerning symptoms to your healthcare provider immediately. If you experience thoughts of self-harm, seek medical attention or call emergency services without delay.

• Dizziness and Movement Coordination Issues: This medication may cause dizziness or coordination problems, especially when starting treatment or increasing the dose. If these symptoms persist or become troublesome, consult your healthcare provider.

• Abnormal Heartbeat: Vimpat can alter heart electrical activity, potentially causing serious heart rhythm issues. This risk is heightened in individuals with pre-existing heart conditions. Inform your healthcare provider and pharmacist about all medications you are taking to avoid interactions. Your provider may perform an electrocardiogram (EKG) prior to and during treatment. Seek medical help if you experience chest pain, palpitations, or fainting sensations.

• Fainting: Rarely, Vimpat may lead to fainting, often due to low blood pressure or irregular heartbeat. Stand up slowly after sitting or lying down. If you feel faint, lie down and elevate your legs. If symptoms persist, seek emergency medical assistance.

• Withdrawal Seizures: Do not discontinue Vimpat abruptly without consulting your healthcare provider, as this can trigger withdrawal seizures. If cessation is necessary, your provider will advise a gradual dose reduction over at least one week.

• Allergic Reactions: Serious allergic reactions, including abnormal blood cell counts and organ damage, have occurred in rare cases. Seek immediate medical attention if you notice symptoms such as rash, fever, swollen lymph nodes, flu-like symptoms, or swelling of the mouth, face, or throat.

• Phenylketonuria (PKU) Consideration: The oral solution form of Vimpat contains aspartame, which can be harmful to individuals with PKU. Consult your provider to determine the suitability of this form if you or your child has PKU.

Please ensure to discuss any concerns or questions with your healthcare provider to ensure safe and effective use of Vimpat.

When taking this medication, you might experience some common side effects as your body adjusts. These include dizziness, headache, nausea, double vision, vomiting, fatigue, blurred vision, sleepiness, and trouble with movement or coordination. Such effects are generally mild and often resolve on their own, but if they persist or worsen, consulting a healthcare provider is advisable.

Other side effects reported by some users include a sensation of the room spinning, difficulty with balance, walking, or memory, and tremors. Some individuals may also notice shaky eye movements, diarrhea, depression, itching, or bruising. While these can be concerning, they are typically manageable with medical advice.

However, it is crucial to be aware of more serious side effects that, although rare, require immediate medical attention. These include suicidal thoughts or self-harm, excessive drowsiness, and abnormal heartbeat, which might manifest as chest discomfort, palpitations, or fainting feelings. Also, watch for severe allergic reactions, such as rash, fever, swollen lymph nodes, flu-like symptoms, swelling of the mouth, face, or throat, dark urine, or yellowing of the skin or eyes. If you experience any of these serious symptoms, seek urgent medical care.