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While using this medication, there is a rare but serious risk of developing severe skin rashes, which can occasionally be life-threatening. These rashes are more prevalent in children than adults and may occur more frequently if:

• The medication is initiated at a high dose.
• The dosage is increased too rapidly.
• It is taken in combination with certain anti-seizure drugs, such as valproic acid or divalproex.

Although rashes can develop at any time, the most severe cases typically appear within 2 to 8 weeks of beginning treatment. Immediate medical attention is essential if you experience a skin rash or other severe allergic reaction symptoms, including:

• Hives
• Fever
• Swollen lymph nodes
• Severe dizziness
• Painful sores in the mouth or around the eyes
• Swelling of the face, tongue, or throat
• Breathing difficulties
• Liver issues, with signs such as persistent stomach or abdominal pain, ongoing nausea or vomiting, dark urine, or yellowing of the eyes or skin.

Consult your healthcare provider to determine whether discontinuation of the medication is necessary. It's important to note that even after stopping the medication, a rash can still develop into a life-threatening condition or lead to permanent scarring or other complications.

You may experience dizziness, drowsiness, headache, vomiting, or an upset stomach when taking this medication. These side effects are generally mild and should not cause alarm. However, if they persist or worsen, it is important to consult with a healthcare professional.

In rare cases, individuals taking anticonvulsants for conditions such as seizures, bipolar disorder, or pain might encounter serious mental health effects, including depression or suicidal thoughts. If you or those around you notice any sudden or unusual changes in mood or behavior, it is crucial to seek medical advice immediately.

Some very serious side effects require urgent medical attention. These include fainting, irregular heartbeat, unusual bruising or bleeding, a stiff neck, vision problems, loss of coordination, muscle pain, or signs of potential kidney issues such as changes in urine output.

This summary does not cover all possible side effects. If you observe any other unusual symptoms, it is advisable to contact a healthcare provider for further guidance.

Some drugs that may interact with this medication include dofetilide and orlistat. Additionally, certain medications can influence how lamotrigine is processed in your body, potentially affecting its effectiveness. Examples include hormonal contraceptives (like pills and patches), estrogens, other seizure medications (such as phenobarbital, primidone, valproic acid), rifampin, and ritonavir. If you are taking these, your doctor might need to adjust your lamotrigine dose.

This medication could reduce the effectiveness of hormonal birth control methods, leading to the possibility of pregnancy. It's important to consult with your doctor or pharmacist about using a reliable backup birth control method while on this medication. Inform your doctor if you experience new spotting or breakthrough bleeding, as these might indicate your birth control is not working effectively.

Let your doctor or pharmacist know if you are using other products that cause drowsiness, including alcohol, cannabis, antihistamines (like cetirizine and diphenhydramine), sleep or anxiety medications (such as alprazolam, diazepam, zolpidem), muscle relaxants, and opioid pain relievers (like codeine).

Be sure to check the labels on all your medications, such as those for allergies or cough and cold, as they might contain ingredients that cause drowsiness. Consult your pharmacist about safely using these products.

This medication may also affect certain laboratory tests, like urine drug screening, possibly leading to incorrect results. Ensure that lab personnel and all your healthcare providers are aware that you are taking this medication.