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This medication comes with several important safety warnings and considerations, which are essential for anyone prescribed tiagabine (Gabitril) to review. It is crucial to discuss any concerns with your healthcare provider.

• Intended Use: Tiagabine is specifically for individuals diagnosed with partial (focal) seizures and should not be used by those without a seizure condition, as it may induce seizures in such individuals.

• Risk of Suicidal Thoughts: There is an increased risk of suicidal thoughts or behavior with the use of antiepileptic drugs like tiagabine. Be vigilant for any signs of new or worsening depression or mood changes, particularly during the initial months of treatment or following a dose adjustment. Immediate medical attention is necessary if you experience thoughts of self-harm.

• Withdrawal Seizures: It is important not to discontinue tiagabine abruptly without medical guidance, as this may trigger withdrawal seizures. If discontinuation is needed, your healthcare provider will provide a tapering schedule to minimize risks.

• Uncontrolled Seizures: On rare occasions, individuals taking tiagabine have experienced uncontrolled seizures (status epilepticus), a condition requiring hospitalization and posing a risk of long-term brain damage. If you have a history of status epilepticus, consult your healthcare provider before starting tiagabine.

• Cognitive and Energy Impairments: Tiagabine can impact cognitive functions, making concentration and communication challenging, and may cause drowsiness and fatigue. Usually mild, these effects should be reported to your provider if persistent or bothersome, as dose adjustments may be beneficial.

• Serious Rash: Although rare, serious rashes have been reported in individuals taking tiagabine. These can be life-threatening, especially if they cover large areas, form blisters, or affect sensitive areas such as the eyes, mouth, or genitals. Seek immediate medical advice if a rash develops.

Keep in mind that there are no specific contraindications noted for tiagabine. Always follow your healthcare provider's instructions and report any adverse effects or concerns promptly.

When taking this medication, some common side effects may occur, which are usually mild and manageable. These include dizziness, experienced by 27% of users, weakness or lack of energy (20%), drowsiness (18%), nausea (11%), and nervousness (10%). If these symptoms persist or worsen, it might be beneficial to discuss them with your healthcare provider.

Other side effects, although less common, can occur and may require attention, especially if they become severe. These include stomach pain, diarrhea, vomiting, increased appetite, or uncontrolled shaking (tremor). Some individuals may experience difficulties with concentration, movement, coordination, walking, or sleeping. Other reported issues include speech or language problems, memory problems, confusion, tingling sensations, depression, mood swings, and feeling unfriendly or agitated. Eye twitching, symptoms similar to a common cold, rash, and itching have also been noted.

In rare cases, more serious side effects can arise, necessitating immediate medical attention. These include thoughts of self-harm or suicide, an increase in seizure activity, and severe rash. Promptly seeking urgent care is crucial if any of these symptoms occur.