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4-Aminopyridine is primarily used to improve walking in patients with multiple sclerosis (MS). It works by blocking potassium channels on nerve cells, which can enhance nerve signal conduction in demyelinated nerves. This can lead to improved motor function in individuals with MS.

The brand name for 4-aminopyridine is Ampyra.

4-Aminopyridine toxicity occurs when there is an excessive amount of 4-aminopyridine in the body, which can lead to a range of symptoms. These symptoms may include seizures, confusion, agitation, tremors, and muscle spasms. In severe cases, it can cause cardiovascular issues such as hypertension and tachycardia. It is important to seek medical attention if toxicity is suspected, as treatment may involve supportive care and medications to manage symptoms.

4-Aminopyridine, also known as dalfampridine, helps individuals with multiple sclerosis (MS) by improving nerve signal conduction. In MS, the protective myelin sheath around nerve fibers is damaged, leading to impaired nerve signal transmission. 4-Aminopyridine works by blocking potassium channels on the nerve cells, which can enhance the conduction of electrical signals along demyelinated nerves. This can lead to improved walking ability and overall mobility in some patients with MS.

4-Aminopyridine is the active ingredient in Ampyra. Ampyra is the brand name for the extended-release formulation of 4-aminopyridine, specifically designed and approved to improve walking in patients with multiple sclerosis. The extended-release formulation helps to maintain a more consistent level of the drug in the bloodstream, which can enhance its therapeutic effects and reduce potential side effects compared to immediate-release versions of 4-aminopyridine.