4-aminopyridine Coupons & Savings Card – Discount Prices from $1.01
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1GM, 4-aminopyridine (1 Bottle)
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$28.38
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$1.01
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$2.95
COUPON PRICE4-aminopyridine savings card
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$1.01
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4-aminopyridine dosage forms
| Dosage | Quantity | Price from | Per unit |
|---|---|---|---|
| 1GM | 1 Bottle | $1.01 | $1.01 |
| 100GM | 1 Bottle | $4575.15 | $4575.15 |
4-aminopyridine Warnings
4-Aminopyridine (4-AP) is a medication used to improve nerve function in certain neurological conditions. While it can be beneficial, it's important to be aware of specific risks associated with its use.
Seizure Risk: 4-AP has been linked to an increased risk of seizures, particularly at higher doses. Individuals with a history of seizures or those with kidney problems, which can lead to higher drug levels in the body, should exercise caution.
Cardiac Concerns: There have been reports of heart-related issues, such as atrial fibrillation (an irregular heartbeat), in individuals taking 4-AP. These events are rare but underscore the need for careful monitoring, especially in those with existing heart conditions.
Compounding Pharmacy Risks: Some patients obtain 4-AP from compounding pharmacies. Errors in compounding can lead to incorrect dosages, resulting in severe toxicity. It's crucial to ensure that any compounded medication comes from a reputable source with strict quality controls.
Environmental and Animal Safety: 4-AP is also used as a bird repellent under the name Avitrol. This use poses risks to non-target animals, including pets, who might accidentally ingest the substance. Such exposure can lead to serious health issues in animals.
Given these risks, it's essential for patients and healthcare providers to discuss the potential dangers of 4-AP, ensure appropriate dosing, and monitor for any adverse effects during treatment.
4-aminopyridine Side Effects
4-Aminopyridine (4-AP) is a medication used to improve walking in adults with multiple sclerosis (MS). While it can be beneficial, it's important to be aware of potential side effects. Common side effects include tingling sensations (paresthesia), dizziness, nausea, and insomnia. Some individuals may also experience balance issues, fatigue, headaches, or urinary tract infections. These effects are generally mild to moderate and often diminish as the body adjusts to the medication. In rare cases, more serious side effects can occur. Seizures have been reported, particularly at higher doses or in individuals with a history of seizures. Other uncommon effects include confusion, memory problems, and heart-related issues such as changes in heart rhythm. It's crucial to inform your healthcare provider about any existing medical conditions, especially kidney problems, as 4-AP is primarily excreted through the kidneys. Impaired kidney function can lead to higher levels of the drug in the body, increasing the risk of side effects. Always follow your healthcare provider's instructions regarding dosage and report any unusual symptoms promptly. Regular monitoring can help ensure the safe and effective use of 4-AP.
4-aminopyridine Interactions
When considering the use of 4-aminopyridine (4-AP), it's important to be aware of potential interactions with other medications:
Medications That Prolong the QT Interval: Combining 4-AP with drugs known to extend the QT interval can increase the risk of serious heart rhythm abnormalities, such as torsade de pointes.
Drugs That Lower Seizure Threshold: Using 4-AP alongside medications that reduce the seizure threshold may heighten the likelihood of seizures.
OCT2 Substrates: Caution is advised when 4-AP is taken with drugs that are substrates of the organic cation transporter 2 (OCT2), including Carvedilol, Propranolol, and Metformin, as interactions may occur.
Additionally, 4-AP is primarily excreted unchanged by the kidneys. Therefore, individuals with significant kidney impairment may experience elevated levels of the drug, increasing the risk of adverse effects.
It's also noteworthy that 4-AP does not significantly inhibit or induce cytochrome P450 enzymes, suggesting a low potential for interactions with medications metabolized by this pathway.
Given these considerations, it's essential to consult with a healthcare provider before starting 4-AP, especially if you are taking other medications or have underlying health conditions.
What does 4-aminopyridine do?
4-Aminopyridine is primarily used to improve walking in patients with multiple sclerosis (MS). It works by blocking potassium channels on nerve cells, which can enhance nerve signal conduction in demyelinated nerves. This can lead to improved motor function in individuals with MS.
What is the brand name for 4-aminopyridine?
The brand name for 4-aminopyridine is Ampyra.
What is 4-aminopyridine toxicity?
4-Aminopyridine toxicity occurs when there is an excessive amount of 4-aminopyridine in the body, which can lead to a range of symptoms. These symptoms may include seizures, confusion, agitation, tremors, and muscle spasms. In severe cases, it can cause cardiovascular issues such as hypertension and tachycardia. It is important to seek medical attention if toxicity is suspected, as treatment may involve supportive care and medications to manage symptoms.
How does 4-aminopyridine help multiple sclerosis?
4-Aminopyridine, also known as dalfampridine, helps individuals with multiple sclerosis (MS) by improving nerve signal conduction. In MS, the protective myelin sheath around nerve fibers is damaged, leading to impaired nerve signal transmission. 4-Aminopyridine works by blocking potassium channels on the nerve cells, which can enhance the conduction of electrical signals along demyelinated nerves. This can lead to improved walking ability and overall mobility in some patients with MS.
What is the difference between 4-aminopyridine and Ampyra?
4-Aminopyridine is the active ingredient in Ampyra. Ampyra is the brand name for the extended-release formulation of 4-aminopyridine, specifically designed and approved to improve walking in patients with multiple sclerosis. The extended-release formulation helps to maintain a more consistent level of the drug in the bloodstream, which can enhance its therapeutic effects and reduce potential side effects compared to immediate-release versions of 4-aminopyridine.