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This safety information outlines crucial warnings and precautions associated with the use of Corlanor (ivabradine). It is essential for patients and healthcare providers to review these points thoroughly to ensure safe use of the medication. Should you have concerns, consult with your healthcare provider.

• Pregnancy Risks: Corlanor (ivabradine) has been shown in animal studies to potentially harm an unborn baby. It is imperative to use effective contraception to prevent pregnancy while taking this medication. Contact your healthcare provider immediately if you become pregnant during treatment.

• Atrial Fibrillation Risk: The use of Corlanor (ivabradine) might increase the likelihood of developing atrial fibrillation, a condition characterized by an irregular heart rhythm. This can lead to serious complications such as blood clots, strokes, or heart attacks. Regular heart monitoring is necessary. Notify your provider if you experience symptoms like lightheadedness, shortness of breath, or a racing heart with chest pressure.

• Bradycardia (Slow Heartbeat): Corlanor (ivabradine) may cause a dangerously slow heart rate, potentially leading to severe heart rhythm disorders. Monitor your heart rate and blood pressure as directed by your healthcare provider. Report any dizziness, extreme fatigue, or abnormally low heart rate or blood pressure to your provider. The risk increases when taken with other heart rate-reducing medications or if certain heart conditions are present.

• Contraindications: Corlanor (ivabradine) should not be used in the following situations, as it may pose significant risks:

  • Acute worsening of heart failure
  • Low blood pressure
  • Sick sinus syndrome (a type of heart rhythm problem)
  • Certain heart block conditions
  • A slow heart rate
  • Presence of a pacemaker
  • Severe liver impairment
  • Concurrent use of CYP3A4 inhibitors

By adhering to these guidelines and maintaining regular consultations with your healthcare provider, you can manage the risks associated with Corlanor (ivabradine) effectively.

When taking this medication, some individuals may experience certain side effects. Commonly reported effects include a slowed heart rate, affecting about 10% of users, and fluctuations in blood pressure, such as increases or high blood pressure, noted in approximately 9% of users. An abnormal heart rhythm known as atrial fibrillation is also observed in around 8% of users. These side effects are generally mild, but if they persist or worsen, it is advisable to consult a healthcare provider for guidance.

In addition, some users have reported experiencing flashes of light or changes in vision. While these side effects are less common, it is important to monitor any developments and seek medical advice if they occur.

There are also rare yet serious side effects associated with this medication. These include irregular heart rhythms, which may manifest as a racing or pounding heart, chest pain or pressure, shortness of breath, dizziness, or fainting. Another serious concern is a significantly slow heart rate, leading to symptoms like dizziness, fatigue, or unexplained lack of energy. In children, this may present as poor feeding, breathing difficulties, or a bluish skin tone. Immediate medical attention is essential if any of these severe symptoms are experienced.