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It is crucial to be aware of the safety information and potential risks associated with the use of Farxiga (dapagliflozin). This medication may pose serious health risks, and patients should consult their healthcare provider with any concerns. Below are the key warnings to consider:

• Ketoacidosis Risk: Farxiga can lead to ketoacidosis, a dangerous condition where excessive ketones make the blood acidic. This risk is heightened if you have diabetes, are ill, consume fewer calories, follow a ketogenic diet, experience dehydration, have pancreatic issues, consume alcohol, or if your insulin dose is reduced or missed, particularly after surgery.

• Dehydration and Low Blood Pressure: The medication may reduce bodily fluids, causing dehydration or low blood pressure. This can impair kidney blood flow and lead to kidney injury. Individuals aged 65 or older, those with kidney problems, or those taking loop diuretics are at increased risk.

• Genital and Urinary Tract Infections: There is an elevated risk of developing genital infections, such as yeast infections, and urinary tract infections (UTIs) with Farxiga. Severe cases may require hospitalization. Symptoms to watch for include fever, painful urination, genital tenderness, redness, itching, or unusual discharge. Treatment might involve antibiotics or antifungals. Those with a history of genital yeast infections or UTIs are at greater risk.

• Hypoglycemia with Other Diabetes Medications: When combined with other diabetes medications like insulin or glipizide, Farxiga can cause dangerously low blood sugar levels (hypoglycemia), which can be life-threatening. Risks increase with changes in diet and exercise, alcohol consumption, and concurrent use of other diabetes medications.

In case of an overdose or any severe adverse reactions, seek immediate medical attention. Always follow your healthcare provider's instructions and inform them about any other medications or conditions that may affect your treatment with Farxiga.

When taking this medication, some common side effects may occur, but they are generally mild and manageable. These include frequent urination, dizziness, lightheadedness, nose and throat infections, and yeast infections in both males and females. To minimize dizziness, try getting up slowly from sitting or lying positions. It is important to stay hydrated to prevent dehydration, which can lead to kidney issues. If you experience symptoms such as an unusual dry mouth, thirst, fast heartbeat, or dizziness, it could indicate dehydration.

Serious side effects, although rare, require immediate medical attention. These include signs of a urinary tract infection such as painful, frequent, or urgent urination, and pink or bloody urine, which can also be symptoms of a rare condition like bladder cancer. Kidney problems might present as changes in urine output or swelling in the legs or feet. Additionally, high blood sugar symptoms like increased thirst and urination, or low blood sugar symptoms such as sudden sweating and shaking, should be addressed promptly.

A rare but severe bacterial infection known as Fournier's gangrene may occur, marked by pain, redness, or swelling in the genital or anal area, accompanied by fever. High ketone levels in the blood, known as ketoacidosis, manifest as fruity breath, dry mouth, and trouble breathing. Severe allergic reactions are very rare but could result in swelling of the face, throat, or tongue, rash, or trouble breathing. If any of these serious symptoms occur, seek urgent medical help. Always inform your healthcare provider if side effects persist or worsen.